SCHEMBL9623360

SCHEMBL9623360

O=S(=O)(CC1CCCC1)CC1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.36
ADRA2C P18825 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM1 P11229 1/20 0.36
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
ALOX5 P09917 2/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13726548 0.87 INPP5A (0.37) INPP5A
SCHEMBL14378258 0.84 CYP1A2 (0.41) CHRM5ADRA2CCHRM2CHRM4CHRM1
SCHEMBL3055263 0.82 CHRM5 (0.34) CHRM5ADRA2CCHRM2CHRM4CHRM1
SCHEMBL2111886 0.79 ADH1B (0.32) ADH1BADH1CADH1AADH4ADH7
SCHEMBL16321334 0.78
SCHEMBL14427012 0.78 CYP1A2 (0.41) CHRM5ADRA2CCHRM2CHRM4CHRM1
SCHEMBL12139970 0.78 EPHX2 (0.33)
SCHEMBL600653 0.77 ADH1B (0.31) ADH1BADH1CADH1AADH4ADH7
SCHEMBL246739 0.77 INPP5A (0.52) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6240484 0.77 ALDH1A1 (0.35) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110902-A High molecular weight polythioether-sulfones PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US disclosed
US-5086163-A High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide PHILLIPS PETROLEUM COMPANY (US) 1992-02-04 US disclosed
US-5015725-A Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings PHILLIPS PETROLEUM COMPANY (US) 1991-05-14 US disclosed
EP-0309955-A1 Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1989-04-05 EP disclosed
US-4125525-A Aromatic sulfide/sulfone polymer production PHILLIPS PETROLEUM COMPANY (US) 1978-11-14 US disclosed