Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645715 | 0.88 | SLC6A9 (0.47) | SLC6A9RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3059626 | 0.71 | SLC6A9 (0.60) | SLC6A9RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3055700 | 0.70 | SLC6A9 (0.59) | SLC6A9RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3059786 | 0.68 | SLC6A9 (0.63) | SLC6A9HPGDKMT2AMEN1 | |
| SCHEMBL2850005 | 0.67 | SLC6A9 (0.54) | SLC6A9RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL13754447 | 0.66 | ALDH1A1 (0.72) | RAB9ANPC1ALDH1A1HPGDJAK2 | |
| SCHEMBL4643557 | 0.66 | KDM4E (0.47) | RAB9ANPC1ALDH1A1HPGDJAK2 | |
| SCHEMBL2458645 | 0.66 | SLC6A12 (0.46) | RAB9ANPC1ALDH1A1HPGDKMT2A | |
| SCHEMBL2460613 | 0.65 | RAB9A (0.47) | RAB9ANPC1ALDH1A1HPGDJAK2 | |
| SCHEMBL29077678 | 0.65 | HPGD (0.71) | RAB9ANPC1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960360-A1 | AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS | MERCK SHARP & DOHME LTD. (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060484-A1 | AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS | MERCK SHARP & DOHME LIMITED (GB) | 2007-05-31 | — | — | WO | disclosed |