Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645164 | 0.90 | MAPT (0.48) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4645248 | 0.85 | LMNA (0.43) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648389 | 0.83 | MAPT (0.42) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648314 | 0.83 | MMP1 (0.57) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648315 | 0.83 | MMP1 (0.57) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648358 | 0.83 | ITGB2 (0.44) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648534 | 0.79 | MAPT (0.41) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648850 | 0.78 | MAOB (0.64) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4648491 | 0.77 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4647175 | 0.76 | NPSR1 (0.40) | MAPTLMNAALDH1A1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |