Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648358 | 0.87 | ITGB2 (0.44) | MAPTLMNAALDH1A1NPSR1HTT | |
| SCHEMBL4647175 | 0.86 | NPSR1 (0.40) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4645248 | 0.81 | LMNA (0.43) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4645164 | 0.80 | MAPT (0.48) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4646530 | 0.79 | RAB9A (0.57) | MAPTALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL4646534 | 0.79 | RAB9A (0.57) | MAPTALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL4646825 | 0.79 | MAPT (0.47) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4648491 | 0.75 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4648389 | 0.73 | MAPT (0.42) | MAPTLMNAALDH1A1NPSR1HPGD | |
| SCHEMBL4644533 | 0.71 | MMP1 (0.61) | MAPTLMNAALDH1A1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |