Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.37 |
| ▸ | HTR3B | O95264 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646923 | 0.92 | HTR3E (0.44) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4645168 | 0.89 | ALDH1A1 (0.39) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4649018 | 0.88 | MAPT (0.35) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4647344 | 0.85 | LMNA (0.47) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4646000 | 0.84 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4645997 | 0.84 | MAPT (0.50) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4645251 | 0.83 | NPSR1 (0.35) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4648393 | 0.83 | MAPT (0.36) | LMNAMAPTALDH1A1NPSR1HTT | |
| SCHEMBL4648580 | 0.83 | LMNA (0.38) | LMNAMAPTALDH1A1NPSR1HTR3E | |
| SCHEMBL4648361 | 0.80 | ITGB2 (0.40) | LMNAMAPTALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |