Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 9/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.40 |
| ▸ | ITGAL | P20701 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648538 | 0.86 | HTR3E (0.32) | MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL4645997 | 0.80 | MAPT (0.50) | MAPTL3MBTL1ALDH1A1LMNANPSR1 | |
| SCHEMBL4646831 | 0.80 | LMNA (0.40) | MAPTL3MBTL1ALDH1A1LMNANPSR1 | |
| SCHEMBL4645168 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL4646889 | 0.78 | CYP1A2 (0.42) | MAPTRAB9AALDH1A1LMNANPSR1 | |
| SCHEMBL4647179 | 0.77 | NOS3 (0.34) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL4646000 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL4646923 | 0.77 | HTR3E (0.44) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL4645251 | 0.77 | NPSR1 (0.35) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL4645534 | 0.76 | MEN1 (0.34) | MAPTL3MBTL1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |