SCHEMBL4646903

SCHEMBL4646903

Nc1cc(O)ccc1S(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.45
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA9 Q16790 2/20 0.45
CA7 P43166 1/20 0.45
CA14 Q9ULX7 1/20 0.45
HSD17B10 Q99714 4/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
ALDH1A1 P00352 4/20 0.44
TTR P02766 1/20 0.42
NQO1 P15559 1/20 0.41
PTGS1 P23219 1/20 0.39
EGFR P00533 1/20 0.39
CASP6 P55212 2/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407028 1.00 CA2 (0.45) CA2CA12CA1CA9CA7
SCHEMBL5156069 0.84 GAA (0.48) CA2CA12CA1CA9CA7
SCHEMBL3494740 0.83 HSD17B10 (0.49) CA2CA12CA1CA9CA7
SCHEMBL343300 0.80 ALDH1A1 (0.50) HSD17B10HPGDAURKAAURKBALDH1A1
SCHEMBL5664509 0.79 LMNA (0.53) HSD17B10LMNAHPGDHIF1AALDH1A1
SCHEMBL11425128 0.79 HSD17B10 (0.41) CA2CA12CA1CA9HSD17B10
SCHEMBL11425210 0.79 TTR (0.53) HSD17B10LMNAHPGDHIF1AAURKA
SCHEMBL7736713 0.79 TTR (0.53) HSD17B10LMNAHPGDHIF1AAURKA
SCHEMBL342537 0.78 ALDH1A1 (0.64) CA2CA12CA1CA9CA7
Ammonia Solution, Strong SCHEMBL7554180 0.78 RAPGEF4 (0.49) HSD17B10HPGDAURKAAURKBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734953-A L-lactate detection kit 北京九强生物技术股份有限公司 2020-01-31 CN claimed
CN-106149408-A A kind of printing inks compositions and the application in calico printing thereof 佛山市柏杰油墨科技有限公司 2016-11-23 CN claimed
CN-103492881-A Assay method REACTIVLAB LTD 2014-01-01 CN claimed
US-20130337481-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2013-12-19 US claimed
EP-2656082-A1 ASSAY METHOD Reactivlab Limited (GB) 2013-10-30 EP claimed
CN-102619108-A Protein reactive ultraviolet absorber and preparation method thereof UNIV ZHEJIANG SCIENCE & TECH 2012-08-01 CN claimed
WO-2012085497-A1 ASSAY METHOD REACTIVLAB LIMITED (GB) 2012-06-28 WO claimed
EP-1031035-B1 HAPTOGLOBIN ASSAY UNIV GLASGOW (GB) 2008-08-20 EP claimed
US-6451550-B1 THE LEVEL OF HAPTOGLOBIN IN A SAMPLE TO BE TESTED IS DETERMINED BY MEASURING THE PEROXIDASE ACTIVITY OF HAPTOGLOBIN/HAEMOGLOBIN COMPLEX. THE ASSAY EMPLOYS AT LEAST ONE REAGENT FOR REDUCING A PEROXIDASE EFFECT DUE TO ANY ANY THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2002-09-17 US claimed
EP-1031035-A1 HAPTOGLOBIN ASSAY THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2000-08-30 EP claimed
EP-0998256-A1 USE OF DI- AND OLIGOACYLAROMATS FOR COLOURING FIBRES CONTAINING KERATIN Henkel Kommanditgesellschaft auf Aktien (DE) 2000-05-10 EP claimed
WO-1999024833-A1 HAPTOGLOBIN ASSAY THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 1999-05-20 WO claimed
WO-1999004754-A1 USE OF DI- AND OLIGOACYLAROMATS FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-02-04 WO claimed
US-12146891-B2 United states systems and methods for fluid and component handling LABRADOR DIAGNOSTICS LLC (US) 2024-11-19 US disclosed
US-12085583-B2 Systems and methods for multi-analysis LABRADOR DIAGNOSTICS LLC (US) 2024-09-10 US disclosed
EP-4220120-A2 SYSTEMS AND METHODS FOR MULTI-ANALYSIS Labrador Diagnostics LLC (US) 2023-08-02 EP disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed
US-4113632-A ALIPHATIC SUBSTITUTED SUCCINIMIDO ARYL HYDROXY SULFONATE OR ITS SUCCINAMIC ACID DERIVATIVE MOBIL OIL CORPORATION (US) 1978-09-12 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed