SCHEMBL4647013

SCHEMBL4647013

CCC[CH]C(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.32
CYP2D6 P10635 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
HTR1A P08908 1/20 0.31
SCN1A P35498 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SCN5A Q14524 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
KMT2A Q03164 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
CYP2C19 P33261 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
HSD11B1 P28845 1/20 0.30
MEN1 O00255 1/20 0.30
ABL1 P00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643573 0.88 MAPT (0.34) MAPTLMNACYP2D6KMT2ACYP2C19
SCHEMBL4644013 0.81 MAPT (0.39) MAPTLMNATDP1KMT2AL3MBTL1
SCHEMBL5973451 0.81 HCAR2 (0.37) MAPTLMNATDP1KMT2AL3MBTL1
SCHEMBL5974325 0.81 HCAR2 (0.37) MAPTLMNATDP1KMT2AL3MBTL1
SCHEMBL5973442 0.81 HCAR2 (0.37) MAPTLMNATDP1KMT2AL3MBTL1
SCHEMBL4647510 0.80 MAPT (0.37) MAPTLMNATDP1KMT2AL3MBTL1
SCHEMBL2189980 0.78 THRB (0.38) MAPTTDP1KMT2ACYP2C19CYP3A4
SCHEMBL28219395 0.77 HCAR2 (0.44) MAPTLMNA
SCHEMBL560570 0.77 ATM (0.51) MAPTTDP1L3MBTL1CYP3A4TSHR
SCHEMBL560045 0.77 ATM (0.51) MAPTTDP1L3MBTL1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed