SCHEMBL4644013

SCHEMBL4644013

CCC[CH]C(=O)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 3/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GLA P06280 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643712 0.86 MAPT (0.38) MAPTLMNAMEN1KMT2ANPC1
SCHEMBL4647013 0.81 MAPT (0.36) MAPTLMNAMEN1KMT2ANPSR1
SCHEMBL4644312 0.78 ALDH1A1 (0.35) MAPTLMNAALDH1A1L3MBTL1TSHR
SCHEMBL4645426 0.77 MAPT (0.41) MAPTLMNAMEN1KMT2ANPC1
SCHEMBL6247098 0.75 ZDHHC2 (0.48) MAPTMEN1KMT2ARAB9AALDH1A1
SCHEMBL4645674 0.74 ATM (0.35) ALDH1A1HPGDTSHR
SCHEMBL28422623 0.73 LMNA (0.37) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL5142114 0.73 THRB (0.43) MAPTLMNAMEN1KMT2AALDH1A1
SCHEMBL2144442 0.72 HCAR2 (0.46) MAPTLMNAKMT2AALDH1A1KDM4E
SCHEMBL2144436 0.72 HCAR2 (0.46) MAPTLMNAKMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed