Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid Ethyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL673371 | 0.88 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28550334 | 0.87 | ALDH1A1 (0.46) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL4647144 | 0.83 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL28118149 | 0.82 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL9403198 | 0.82 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL28604855 | 0.82 | TSHR (0.52) | TSHRHPGDTHRBALDH1A1TP53 | |
| Tert-Butylamine SCHEMBL4190210 | 0.82 | CA2 (0.46) | HPGDALDH1A1TP53SMN1; SMN2HSD17B10 | |
| Acrylic Acid Ethyl Ester SCHEMBL28294928 | 0.80 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28257852 | 0.80 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL28372681 | 0.80 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687348-B1 | COPOLYMERS COMPRISING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS | BASF SE (DE) | 2008-11-12 | — | — | EP | claimed |
| EP-3467086-B1 | DISHWASHING CLEANING COMPOSITION | PROCTER & GAMBLE (US) | 2021-03-24 | — | — | EP | disclosed |
| US-10815327-B2 | Copolymers comprising polyalkylene oxide groups and quaternary nitrogen atoms | BASF SE (DE) | 2020-10-27 | — | — | US | disclosed |
| US-10731106-B2 | Dishwashing cleaning composition | THE PROCTER & GAMBLE COMPANY (US) | 2020-08-04 | — | — | US | disclosed |
| US-10723979-B2 | Dishwashing cleaning composition | THE PROCTER & GAMBLE COMPANY (US) | 2020-07-28 | — | — | US | disclosed |
| EP-3440121-B1 | COPOLYMERS COMPRISING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS | BASF SE (DE) | 2020-05-06 | — | — | EP | disclosed |
| EP-3228687-B1 | DISHWASHING CLEANING COMPOSITION | PROCTER & GAMBLE (US) | 2019-05-22 | — | — | EP | disclosed |
| WO-2019070923-A1 | DISHWASHING CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2019-04-11 | — | — | WO | disclosed |
| US-20190106658-A1 | DISHWASHING CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2019-04-11 | — | — | US | disclosed |
| US-20190106655-A1 | DISHWASHING CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2019-04-11 | — | — | US | disclosed |
| EP-3440121-A1 | COPOLYMERS COMPRISING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS | BASF SE (DE) | 2019-02-13 | — | — | EP | disclosed |
| US-20170292093-A1 | DISHWASHING CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2017-10-12 | — | — | US | disclosed |
| WO-2017174468-A1 | COPOLYMERS COMPRISING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS | BASF SE (DE) | 2017-10-12 | — | — | WO | disclosed |
| WO-2017176500-A1 | DISHWASHING CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2017-10-12 | — | — | WO | disclosed |
| EP-3228687-A1 | DISHWASHING CLEANING COMPOSITION | The Procter and Gamble Company (US) | 2017-10-11 | — | — | EP | disclosed |
| EP-1685227-B1 | LAUNDRY COMPOSITIONS HAVING COPOLYMERS CONTAINING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS AND A SURFACTANT SYSTEM | PROCTER & GAMBLE (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20070129516-A1 | Copolymers comprising polyalkylene oxide groups and quaternary nitrogen atoms | DETERING JUERGEN | 2007-06-07 | — | — | US | disclosed |
| EP-1685227-A1 | LAUNDRY COMPOSITIONS HAVING COPOLYMERS CONTAINING POLYALKYLENE OXIDE GROUPS AND QUATERNARY NITROGEN ATOMS AND A SURFACTANT SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052107-A1 | LAUNDRY COMPOSITIONS HAVING COPOLYMERS CONTAINING POLYALKYLENE OXIDE GROUPS AND QUANTERNARY NITROGEN ATOMS AND A SURFACTANT SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113280-A1 | Laundry compositions having copolymers containing polyalkylene oxide groups and quaternary nitrogen atoms and a surfactant system | PROCTER & GAMBLE COMPANY, THE | 2005-05-26 | — | — | US | disclosed |