SCHEMBL4647895

SCHEMBL4647895

c1cc(CC2CS2)cc(CC2CS2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 2/20 0.35
SIGMAR1 Q99720 2/20 0.35
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
GLA P06280 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
MMP2 P08253 2/20 0.30
MMP9 P14780 2/20 0.30
MMP14 P50281 2/20 0.30
MMP3 P08254 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916462 0.83 GBA1 (0.43) TMEM97SIGMAR1
SCHEMBL4644559 0.79 MMP2 (0.33) TMEM97SIGMAR1MMP2MMP9MMP14
SCHEMBL5209778 0.76
SCHEMBL4989552 0.73 HRH3 (0.36) MEN1KMT2AMMP2MMP9MMP14
SCHEMBL4992502 0.73 ALDH1A1 (0.36) TMEM97SIGMAR1ESR1ESR2MEN1
SCHEMBL4742114 0.73
SCHEMBL1402639 0.73 SLC11A2 (0.36) ACHEMEN1KMT2ACYP1A2SMN1; SMN2
SCHEMBL1402494 0.73 TSHR (0.37) BCHEACHE
SCHEMBL1093206 0.71 SLC11A2 (0.35)
SCHEMBL9150 0.69 TMEM97 (0.44) TMEM97SIGMAR1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1962139-A1 Negative resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-08-27 EP disclosed