SCHEMBL9150

SCHEMBL9150

c1ccc(CC2CSCCS2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 3/20 0.44
SIGMAR1 Q99720 3/20 0.44
GBA1 P04062 1/20 0.36
ACE P12821 1/20 0.36
FAAH O00519 1/20 0.35
POLB P06746 3/20 0.34
ALDH1A1 P00352 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916462 0.83 GBA1 (0.43) TMEM97SIGMAR1GBA1ACEPOLB
SCHEMBL8998 0.74 FAAH (0.43) GBA1ACEFAAHPOLB
SCHEMBL28090 0.73 POLB (0.44) GBA1FAAHPOLB
SCHEMBL450052 0.73 GBA1 (0.42) GBA1FAAHPOLB
SCHEMBL317332 0.72 TAAR1 (0.38) GBA1ACEPOLBNPC1RAB9A
SCHEMBL4644559 0.71 MMP2 (0.33) TMEM97SIGMAR1ACE
SCHEMBL20842916 0.71 GBA1 (0.50) TMEM97SIGMAR1GBA1ALDH1A1
SCHEMBL9185438 0.70 GBA1 (0.34) TMEM97SIGMAR1GBA1ACEFAAH
SCHEMBL694287 0.70 MAOB (0.48) GBA1POLB
SCHEMBL22206478 0.69 GBA1 (0.44) TMEM97SIGMAR1GBA1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1847 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109952652-B Imaging element, stacked imaging element, imaging device, and electronic device 索尼公司 2023-09-19 CN claimed
EP-3245198-B1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS NOVARTIS AG (CH) 2020-03-11 EP claimed
US-10065943-B2 Pyrrolidine derivatives as angiotensin II type 2 antagonists NOVARTIS AG (CH) 2018-09-04 US claimed
US-20170369473-A1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS SPINIFEX PHARMACEUTICALS PTY LTD (AU) 2017-12-28 US claimed
EP-3245198-A1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS Novartis AG (CH) 2017-11-22 EP claimed
WO-2016113668-A1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS NOVARTIS AG (CH) 2016-07-21 WO claimed
EP-1852420-B1 Indole compounds for treating respiratory disorders ONO PHARMACEUTICAL CO (JP) 2012-10-17 EP claimed
US-7402580-B2 Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2008-07-22 US claimed
US-6036888-A ADDING SULFUR-CONTAINING HETEROCYCLIC RING COMPOUNDS TO AQUEOUS ALKANOLAMINE SOLUTION TO INHIBIT CORROSION OF METALS IN ACID GAS RICH AND ACID GAS LEAN PORTIONS OF AN ACID GAS REMOVAL UNIT BETZDEARBORN INC. (US) 2000-03-14 US claimed
WO-1999010561-A1 CORROSION INHIBITOR FOR ALKANOLAMINE UNITS BETZDEARBORN INC. (US) 1999-03-04 WO claimed
EP-0790983-A1 PESTICIDAL PYRIDINE THIOAMIDES Novartis AG (CH) 1997-08-27 EP claimed
WO-1996014301-A1 PESTICIDAL PYRIDINE THIOAMIDES NOVARTIS AG (CH) 1996-05-17 WO claimed
US-5403936-A Irradiating organic optical material comprising oxazoline derivative with light KABUSHIKI KAISHA TOSHIBA (JP) 1995-04-04 US claimed
US-12630510-B2 EP2 antagonist ONO PHARMACEUTICAL CO., LTD. (JP) 2026-05-19 US disclosed
EP-4727924-A1 INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION ONO Pharmaceutical Co., Ltd. (JP) 2026-04-22 EP disclosed
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ONO PHARMACEUTICAL CO., LTD. (JP) 2026-04-14 US disclosed
US-5332648-A Alklali soluble phenolic polymer, cyclic ester or sulfonate which converts to the acid, an onium salt which generates an an acid on exposure to radiation KABUSHIKI KAISHA TOSHIBA (JP) 1994-07-26 US disclosed
EP-0422900-B1 Organic nonlinear optical material and nonlinear optical element TOSHIBA KK (JP) 1994-03-16 EP disclosed
US-5279921-A Pattern formation resist and pattern formation method KABUSHIKI KAISHA TOSHIBA (JP) 1994-01-18 US disclosed
EP-0422900-A2 Organic nonlinear optical material and nonlinear optical element KABUSHIKI KAISHA TOSHIBA (JP) 1991-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369473-A1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS AGTR2, AGTR1, AVPR2 TMEM97 2725/4885SIGMAR1 1124/4885GBA1 4732/4885
US-10065943-B2 Pyrrolidine derivatives as angiotensin II type 2 antagonists AGTR2, AGTR1, ACE2 TMEM97 2217/4885SIGMAR1 759/4885GBA1 4568/4885
US-12630510-B2 EP2 antagonist PTGER2, PTGER1, PTGER4 TMEM97 511/4885SIGMAR1 59/4885GBA1 2136/4885
US-12600730-B2 Substituted cyclopenta[c]pyrroles as ABHD6 antagonists ABHD6, ABHD16A, HDHD5 TMEM97 1266/4885SIGMAR1 1317/4885GBA1 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.