SCHEMBL9404141

SCHEMBL9404141

CC(OC(=O)Cl)c1c2ccccc2cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
KDM4E B2RXH2 6/20 0.42
HPGD P15428 5/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GLA P06280 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NCEH1 Q6PIU2 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
AKR1B1 P15121 1/20 0.37
TP53 P04637 1/20 0.36
ERN1 O75460 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29853852 0.85 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL4648011 0.85 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL12383183 0.82 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL9404103 0.80 MEN1 (0.39) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL11636414 0.80 HCAR2 (0.39) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5594212 0.80 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL2740643 0.78 KMT2A (0.40) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL9404136 0.76 L3MBTL1 (0.43) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL2740653 0.76 RIPK1 (0.39) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL12269094 0.75 SMN1; SMN2 (0.46) ALDH1A1HPGDMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365495-B1 9-Anthrylalkyl compounds, their preparation and their use EKA NOBEL AB (SE) 1994-03-16 EP disclosed
US-5128120-A Use of 9-anthrylalkyl compounds as derivatization reagents for separation and detection purposes EKA NOBEL AB (SE) 1992-07-07 US disclosed
US-5015755-A 9-anthrylalkyl compounds EKA NOBEL AB (SE) 1991-05-14 US disclosed
EP-0365495-A2 9-Anthrylalkyl compounds, their preparation and their use Eka Nobel Aktiebolag (SE) 1990-04-25 EP disclosed