Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485894 | 0.80 | NPC1 (0.57) | NPC1RAB9AALDH1A1MAPTHDAC3 | |
| SCHEMBL265422 | 0.80 | NPC1 (0.57) | NPC1RAB9AALDH1A1MAPTHDAC3 | |
| SCHEMBL4649057 | 0.77 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL1568799 | 0.74 | NPC1 (0.59) | NPC1RAB9AALDH1A1HDAC3HDAC4 | |
| SCHEMBL5692234 | 0.73 | NPC1 (0.50) | NPC1RAB9AMAPTHTTHDAC3 | |
| SCHEMBL7410536 | 0.73 | NPC1 (0.57) | NPC1RAB9AALDH1A1HDAC3HDAC4 | |
| SCHEMBL27752011 | 0.72 | NPC1 (0.49) | NPC1RAB9AALDH1A1HDAC3HDAC4 | |
| SCHEMBL295136 | 0.71 | NPC1 (0.69) | NPC1RAB9AALDH1A1HDAC3EPHX2 | |
| SCHEMBL1990363 | 0.71 | NPC1 (0.69) | NPC1RAB9AALDH1A1HDAC3EPHX2 | |
| SCHEMBL20697899 | 0.71 | HCAR2 (0.55) | NPC1RAB9AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |