Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 9/20 | 0.36 |
| ▸ | METAP1 | P53582 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15442392 | 0.85 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL15442389 | 0.80 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL4648336 | 0.77 | NPC1 (0.50) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL9923613 | 0.76 | MAPT (0.58) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL9923615 | 0.76 | MAPT (0.58) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL29486039 | 0.76 | MTNR1A (0.42) | ALDH1A1LMNAMAPTMETAP2METAP1 | |
| SCHEMBL4648121 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL3986444 | 0.75 | MAPT (0.56) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL9277123 | 0.75 | MAPT (0.56) | ALDH1A1LMNAMAPTNPSR1PLIN1 | |
| SCHEMBL10436437 | 0.75 | HDAC2 (0.61) | ALDH1A1LMNAMAPTPLIN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |