Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 2/20 | 0.49 |
| ▸ | CA6 | P23280 | 2/20 | 0.49 |
| ▸ | CA5A | P35218 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16237381 | 0.81 | DAO (0.37) | CA2CA12CA1CA3CA4 | |
| SCHEMBL21962066 | 0.80 | CA2 (0.45) | CA2CA12CA1CA5ACA7 | |
| SCHEMBL9429522 | 0.78 | DAO (0.55) | CA2CA12CA1CA3CA4 | |
| SCHEMBL5524092 | 0.76 | CA2 (0.44) | CA2CA1CA3CA9LMNA | |
| SCHEMBL4648825 | 0.74 | TSHR (0.39) | CA2CA12CA1CA3CA4 | |
| SCHEMBL623602 | 0.71 | TSHR (0.45) | CA2CA12CA1CA3CA4 | |
| SCHEMBL5512490 | 0.71 | CA2 (0.40) | CA2 | |
| SCHEMBL2345395 | 0.71 | CA2 (0.41) | CA2CA12CA1CA3CA4 | |
| Hydrochloric Acid SCHEMBL29045760 | 0.70 | TSHR (0.43) | CA2CA12CA1CA3CA4 | |
| SCHEMBL2825614 | 0.68 | ALDH1A1 (0.53) | TSHRHSD17B10AKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959964-A1 | HETEROAROMATIC SULFONAMIDE PRODRUGS | Bayer Schering Pharma AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-20070135399-A1 | Heteroaromatic sulphonamide prodrugs | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-14 | — | — | US | disclosed |
| WO-2007062875-A1 | HETEROAROMATIC SULFONAMIDE PRODRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135399-A1 | Heteroaromatic sulphonamide prodrugs | SULT2A1, SULT1E1, SULT1A1 | CA2 29/4885CA12 407/4885CA1 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.