Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.75 |
| ▸ | CA2 | P00918 | 2/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | CA3 | P07451 | 1/20 | 0.75 |
| ▸ | CA4 | P22748 | 1/20 | 0.75 |
| ▸ | CA6 | P23280 | 1/20 | 0.75 |
| ▸ | CA5A | P35218 | 1/20 | 0.75 |
| ▸ | CA7 | P43166 | 1/20 | 0.75 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.75 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.75 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.75 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818550 | 1.00 | CA1 (0.75) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12168543 | 0.96 | CA1 (0.70) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12168553 | 0.94 | SCN9A (0.67) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12188562 | 0.94 | CA1 (0.67) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12168550 | 0.93 | CA12 (0.65) | CA1CA2CA12CA3CA4 | |
| SCHEMBL993730 | 0.91 | CA12 (0.62) | CA1CA2CA12CA3CA4 | |
| SCHEMBL993731 | 0.91 | CA12 (0.62) | CA1CA2CA12CA3CA4 | |
| SCHEMBL2858060 | 0.88 | CA1 (0.59) | CA1CA2CA12CA3CA4 | |
| SCHEMBL2862880 | 0.88 | CA1 (0.59) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12168520 | 0.87 | CA1 (0.77) | CA1CA2CA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140712-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | NEKTAR THERAPEUTICS | 2018-05-24 | — | — | US | claimed |
| US-20170165372-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | NEKTAR THERAPEUTICS | 2017-06-15 | — | — | US | claimed |
| EP-2035029-B1 | PEPTIDE COMPOUNDS FOR TREATING REFRACTORY STATUS EPILEPTICUS | UCB PHARMA GMBH (DE) | 2016-11-30 | — | — | EP | claimed |
| US-20140296334-A1 | N-Optionally Substituted Aryl-2-Oligomer-3-Alkoxypropionamides | NEKTAR THERAPEUTICS | 2014-10-02 | — | — | US | claimed |
| EP-2046386-B1 | PEPTIDE COMPOUNDS FOR THE TREATMENT OF SKELETAL MUSCLE DISORDERS ASSOCIATED WITH ION CHANNEL DYSFUNCTION | UCB PHARMA GMBH (DE) | 2014-07-23 | — | — | EP | claimed |
| US-20140128377-A1 | METHODS OF TREATING REFRACTORY REPETITIVE SEIZURES | UCB PHARMA GMBH (DE) | 2014-05-08 | — | — | US | claimed |
| US-20140066515-A1 | METHODS FOR TREATING CHANNELOPATHIES | UCB PHARMA GMBH (DE) | 2014-03-06 | — | — | US | claimed |
| US-20130316953-A1 | NEW USES FOR AMINO ACID ANTICONVULSANTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2013-11-28 | — | — | US | claimed |
| EP-2210598-B1 | Anticonvulsant amino acids for the treatment of pain | RES CORP TECHNOLOGIES INC (US) | 2013-09-18 | — | — | EP | claimed |
| US-8519183-B2 | Uses for amino acid anticonvulsants | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2013-08-27 | — | — | US | claimed |
| US-6803481-B2 | TREATING DIFFERENT TYPES AND SYMPTOMS OF ACUTE AND CHRONIC PAIN, ESPECIALLY NON NEUROPATHIC INFLAMMATORY PAIN IN MAMMALS. THE PAIN TO BE TREATED MAY BE E.G. CHRONIC INFLAMMATORY PAIN, RHEUMATOID ARTHRITIS PAIN AND/OR SECONDARY | SCHWARZ PHARMA AG (DE) | 2004-10-12 | — | — | US | claimed |
| US-20040097416-A1 | New uses for amino acid anticonvulsants | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2004-05-20 | — | — | US | claimed |
| US-20040087508-A1 | Users for amino acid anticonvulsants | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2004-05-06 | — | — | US | claimed |
| EP-1373300-A2 | NOVEL USE OF A PEPTIDE CLASS OF COMPOUND FOR TREATING NON NEUROPATHIC INFLAMMATORY PAIN | SCHWARZ PHARMA AG (DE) | 2004-01-02 | — | — | EP | claimed |
| EP-1365787-A2 | NEW USES FOR AMINO ACID ANTICONVULSANTS FOR TREATMENT OF PAIN | Research Corporation Technologies, Inc (US) | 2003-12-03 | — | — | EP | claimed |
| US-20030171300-A1 | Treating different types and symptoms of acute and chronic pain, especially non neuropathic inflammatory pain in mammals. The pain to be treated may be e.g. chronic inflammatory pain, rheumatoid arthritis pain and/or secondary | UCB PHARMA GMBH (DE) | 2003-09-11 | — | — | US | claimed |
| WO-2002074784-A2 | NOVEL USE OF A PEPTIDE CLASS OF COMPOUND FOR TREATING NON NEUROPATHIC INFLAMMATORY PAIN | SCHWARZ PHARMA AG (DE) | 2002-09-26 | — | — | WO | claimed |
| EP-1243262-A1 | Novel use of a peptide class of compound for treating non-neuropathic inflammatory pain | SCHWARZ PHARMA AG (DE) | 2002-09-25 | — | — | EP | claimed |
| US-20020086828-A1 | Uses for amino acid anticonvulsants | HARRIS ROBERT H (US) | 2002-07-04 | — | — | US | claimed |
| WO-2002015922-A2 | NEW USES FOR AMINO ACID ANTICONVULSANTS FOR TREATMENT OF PAIN | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2002-02-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086828-A1 | Uses for amino acid anticonvulsants | SLC1A2, SLC1A1, SLC1A3 | CA1 743/4885CA2 330/4885CA12 897/4885 |
| US-20140066515-A1 | METHODS FOR TREATING CHANNELOPATHIES | HCN3, KCNN3, KCNN2 | CA1 1323/4885CA2 407/4885CA12 3479/4885 |
| US-20040087508-A1 | Users for amino acid anticonvulsants | SLC1A2, SLC1A1, SLC1A3 | CA1 1106/4885CA2 930/4885CA12 1396/4885 |
| US-20130316953-A1 | NEW USES FOR AMINO ACID ANTICONVULSANTS | SLC1A2, SLC1A1, SLC1A3 | CA1 832/4885CA2 383/4885CA12 886/4885 |
| US-20040097416-A1 | New uses for amino acid anticonvulsants | SLC1A2, SLC1A1, SLC1A3 | CA1 780/4885CA2 487/4885CA12 1055/4885 |
| US-20140128377-A1 | METHODS OF TREATING REFRACTORY REPETITIVE SEIZURES | GABRE, GRIK2, GABRR1 | CA1 60/4885CA2 312/4885CA12 624/4885 |
| US-20180140712-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | UGT1A3, AADAC, ATXN2 | CA1 4152/4885CA2 4346/4885CA12 2052/4885 |
| US-20170165372-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | UGT1A3, AADAC, ATXN2 | CA1 4152/4885CA2 4346/4885CA12 2052/4885 |
| US-20140296334-A1 | N-Optionally Substituted Aryl-2-Oligomer-3-Alkoxypropionamides | UGT1A3, AADAC, ATXN2 | CA1 4152/4885CA2 4346/4885CA12 2052/4885 |
| US-20030171300-A1 | Treating different types and symptoms of acute and chronic pain, especially non neuropathic inflammatory pain in mammals. The pain to be treated may be e.g. chronic inflammatory pain, rheumatoid arthritis pain and/or secondary | OPRK1, OPRL1, PTGER1 | CA1 2279/4885CA2 1974/4885CA12 3621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.