Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579130 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9959446 | 0.70 | ALDH1A1 (0.56) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL3670519 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL27973531 | 0.68 | ACLY (0.55) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7627388 | 0.66 | KEAP1 (0.67) | ALDH1A1MEN1KMT2ADUSP3PTPN5 | |
| SCHEMBL18862467 | 0.65 | KDM4E (0.60) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9954267 | 0.65 | SLC22A12 (0.55) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL22804020 | 0.64 | MET (0.65) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL29948327 | 0.64 | MET (0.65) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6431253 | 0.64 | KEAP1 (0.57) | KDM4EALDH1A1MEN1KMT2AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904490-A1 | ETHANOLAMINE SALT OF N- (3-METHOXY-5-METHYLPYRAZIN-2YL) -2- (4- [1 , 3 , 4-0XADIAZ0LE-2-YL]PHENYL) PYRIDINE-3- SULPHONAMIDE | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | claimed |
| WO-2007010235-A1 | ETHANOLAMINE SALT OF N- (3-METHOXY-5-METHYLPYRAZIN-2YL) -2- (4- [1 , 3 , 4-0XADIAZ0LE-2-YL] PHENYL) PYRIDINE-3- SULPHONAMIDE | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | claimed |