Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779571 | 0.91 | NPBWR1 (0.58) | NPBWR1ALDH1A1NPSR1MCHR1LTA4H | |
| SCHEMBL14282366 | 0.90 | NPBWR1 (0.51) | NPBWR1ALDH1A1NPSR1MCHR1HTR1A | |
| SCHEMBL14282280 | 0.90 | NPBWR1 (0.53) | NPBWR1ALDH1A1NPSR1MCHR1LTA4H | |
| SCHEMBL14282443 | 0.90 | MCHR1 (0.47) | NPBWR1ALDH1A1NPSR1MCHR1LTA4H | |
| SCHEMBL4670687 | 0.90 | MCHR1 (0.61) | NPBWR1ALDH1A1NPSR1MCHR1CYP1A2 | |
| SCHEMBL14282372 | 0.89 | NPBWR1 (0.48) | NPBWR1ALDH1A1NPSR1MCHR1LTA4H | |
| SCHEMBL4673910 | 0.88 | NPBWR1 (0.52) | NPBWR1ALDH1A1NPSR1MCHR1HTR1A | |
| SCHEMBL14282426 | 0.87 | NPBWR1 (0.55) | NPBWR1ALDH1A1MCHR1LTA4HHTR1A | |
| SCHEMBL4670163 | 0.87 | NPBWR1 (0.53) | NPBWR1ALDH1A1NPSR1MCHR1CYP1A2 | |
| SCHEMBL14282445 | 0.87 | MCHR1 (0.50) | NPBWR1ALDH1A1NPSR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080292547-A1 | Novel Imaging Agents for Fibrosis | TOLLESHAUG HELGE | 2008-11-27 | — | — | US | disclosed |
| EP-1962911-A2 | NOVEL IMAGING AGENTS FOR FIBROSIS | GE Healthcare Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066119-A2 | NOVEL IMAGING AGENTS FOR FIBROSIS | GE HEALTHCARE LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080292547-A1 | Novel Imaging Agents for Fibrosis | LOXL1, LOXL2, LOXL3 | NPBWR1 733/4885ALDH1A1 845/4885NPSR1 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.