Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706811 | 0.86 | ACE (0.47) | SMN1; SMN2LMNAPOLBGBA2PREP | |
| SCHEMBL30565290 | 0.82 | LMNA (0.38) | SMN1; SMN2LMNAPOLBGBA2PREP | |
| SCHEMBL16619795 | 0.81 | GBA2 (0.46) | SMN1; SMN2LMNAPOLBGBA2ALDH1A1 | |
| SCHEMBL14232848 | 0.80 | LMNA (0.42) | SMN1; SMN2LMNAPOLBGBA2PREP | |
| SCHEMBL200924 | 0.79 | RAB9A (0.46) | HSD17B10NPSR1POLBPREPALDH1A1 | |
| SCHEMBL8141816 | 0.76 | FKBP1A (0.48) | SMN1; SMN2LMNAPOLBL3MBTL1NPC1 | |
| SCHEMBL3656325 | 0.76 | FKBP1A (0.48) | SMN1; SMN2LMNAPOLBL3MBTL1NPC1 | |
| SCHEMBL5727740 | 0.76 | FKBP1A (0.48) | SMN1; SMN2LMNAPOLBL3MBTL1NPC1 | |
| SCHEMBL17293189 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAPOLBGBA2ALDH1A1 | |
| SCHEMBL11342331 | 0.75 | HSD17B10 (0.51) | HSD17B10NPSR1ALDH1A1ACEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963262-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007069020-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-06-21 | — | — | WO | disclosed |