Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648863 | 0.97 | PARP15 (0.47) | PARP15PARP10SLC2A1PARP2FNTA | |
| SCHEMBL5653131 | 0.84 | CYP1A2 (0.46) | PARP10FFAR1EPORALOX5PTGES | |
| SCHEMBL5653525 | 0.80 | SRD5A2 (0.44) | PARP10FFAR1ALOX5PTGESLPAR1 | |
| SCHEMBL27826145 | 0.78 | TRPM8 (0.46) | EPORTRPM8 | |
| SCHEMBL2246642 | 0.77 | MMP12 (0.41) | FFAR1ALOX5PTGES | |
| SCHEMBL4369489 | 0.76 | PTGES (0.45) | FFAR1ALOX5PTGES | |
| SCHEMBL4367868 | 0.75 | TSHR (0.43) | FFAR1CHEK2TRPM8 | |
| SCHEMBL5652505 | 0.75 | KMT2A (0.40) | EPORTRPM8 | |
| SCHEMBL4365889 | 0.74 | PTGES (0.45) | ALOX5PTGESTRPM8LPAR1 | |
| SCHEMBL2245542 | 0.74 | PARP15 (0.54) | PARP15PARP10PARP2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | claimed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | claimed |