Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070873 | 0.87 | PKM (0.56) | SIGMAR1CNR2LMNADRD2DRD3 | |
| SCHEMBL27966164 | 0.85 | SIGMAR1 (0.62) | SIGMAR1CNR2MAOBKMT2A | |
| SCHEMBL4488918 | 0.85 | HRH3 (0.67) | CNR2KMT2ASMN1; SMN2 | |
| SCHEMBL7695910 | 0.82 | ACHE (0.72) | KMT2A | |
| SCHEMBL4651287 | 0.82 | CNR2 (0.64) | SIGMAR1CNR2LMNAPOLBMC4R | |
| SCHEMBL16226080 | 0.81 | SIGMAR1 (0.78) | SIGMAR1LMNAPOLBDRD4MC4R | |
| SCHEMBL4475494 | 0.80 | CNR2 (0.54) | SIGMAR1CNR2 | |
| SCHEMBL4475484 | 0.80 | CNR2 (0.54) | SIGMAR1CNR2 | |
| SCHEMBL3041365 | 0.80 | S1PR5 (0.68) | SIGMAR1CNR2 | |
| SCHEMBL13708759 | 0.79 | CNR2 (0.70) | SIGMAR1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |