Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649570 | 0.87 | SIGMAR1 (0.62) | CNR2DRD2DRD3SIGMAR1MAOB | |
| Hydrochloric Acid SCHEMBL8804632 | 0.85 | SMN1; SMN2 (0.51) | CNR2ALDH1A1DRD2DRD3SIGMAR1 | |
| SCHEMBL24023496 | 0.84 | CHKA (0.62) | PKMALDH1A1SIGMAR1LMNA | |
| SCHEMBL8070876 | 0.81 | LSS (0.63) | PKMALDH1A1SIGMAR1LMNAMEN1 | |
| SCHEMBL11347486 | 0.80 | SIGMAR1 (0.72) | PKMALDH1A1SIGMAR1LMNAKMT2A | |
| SCHEMBL3037947 | 0.80 | SIGMAR1 (0.72) | PKMALDH1A1SIGMAR1LMNAKMT2A | |
| SCHEMBL4488918 | 0.80 | HRH3 (0.67) | CNR2ALDH1A1MEN1NPC1TP53 | |
| SCHEMBL27966164 | 0.80 | SIGMAR1 (0.62) | CNR2SIGMAR1MAOBMEN1KMT2A | |
| SCHEMBL8059627 | 0.80 | HRH1 (0.52) | CNR2ALDH1A1DRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8804621 | 0.80 | CNR2 (0.42) | CNR2ALDH1A1MAOBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046332-A | Methods for the manufacture of cetirizine | TAO YONG (CA) | 2000-04-04 | — | — | US | disclosed |
| WO-1998002425-A1 | METHODS FOR THE MANUFACTURE OF CETIRIZINE | APOTEX INC. (CA) | 1998-01-22 | — | — | WO | disclosed |