Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 7/20 | 0.36 |
| ▸ | NOS1 | P29475 | 7/20 | 0.36 |
| ▸ | NOS2 | P35228 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649152 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL22477358 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL5011983 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL15743712 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL4611302 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL14993410 | 0.95 | NOS3 (0.41) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL15665415 | 0.93 | NISCH (0.40) | NISCHNOS3NOS1NOS2HSD17B10 | |
| SCHEMBL6498120 | 0.93 | NOS1 (0.39) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL15526124 | 0.91 | NISCH (0.39) | NISCHNOS3NOS1NOS2MEN1 | |
| SCHEMBL14993640 | 0.91 | NISCH (0.39) | NISCHNOS3NOS1NOS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785726-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | Dow Corning Corporation (US) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013081820-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW CORNING CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-1963388-A1 | POLYURETHANE ELASTOMERS COMPRISING ALLOPHANATE MODIFIED ISOCYANATES | Bayer MaterialScience LLC (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1963390-A1 | RIM ELASTOMERS BASED ON ISOCYANURATES OF ISOPHORONE DIISOCYANATE AND PREPOLYMERS THEREOF | Bayer MaterialScience LLC (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007075329-A1 | RIM ELASTOMERS BASED ON ISOCYANURATES OF ISOPHORONE DIISOCYANATE AND PREPOLYMERS THEREOF | BAYER MATERIALSCIENCE LLC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075330-A1 | POLYURETHANE ELASTOMERS COMPRISING ALLOPHANATE MODIFIED ISOCYANATES | BAYER MATERIALSCIENCE LLC (US) | 2007-07-05 | — | — | WO | disclosed |