SCHEMBL465010

SCHEMBL465010

C=C[Si](O)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
AKT1 P31749 1/20 0.36
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
ALOX15 P16050 1/20 0.33
TGM2 P21980 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
MAPT P10636 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B2 P19099 1/20 0.31
NOTUM Q6P988 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352107 0.79 TSHR (0.38) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL3853122 0.79 TSHR (0.38) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL464990 0.75 ESR1 (0.41) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL3321240 0.73 TSHR (0.33) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL160241 0.72 ALDH1A1 (0.41) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL1674781 0.72 ALDH1A1 (0.41) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL226240 0.72 ALDH1A1 (0.41) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL2288347 0.70 MAPT (0.34) TSHRALDH1A1AKT1ESR1ESR2
SCHEMBL18610644 0.70 MAPT (0.37) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL4354899 0.69 ALDH1A1 (0.30) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268489-B2 Non-aqueous electrolyte solution for lithium secondary battery and lithium secondary battery comprising the same LG CHEM, LTD. (KR) 2012-09-18 US claimed
US-20110206999-A1 NON-AQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-08-25 US claimed
EP-3608367-B1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION AND BASE MATERIAL SHINETSU CHEMICAL CO (JP) 2024-07-10 EP disclosed
CN-118027090-A Method for generating silanol by oxidizing silane 吉林大学 2024-05-14 CN disclosed
CN-111278926-B Curable silicone composition, resin sheet for optical member containing same, and light-emitting device 陶氏东丽株式会社 2022-06-07 CN disclosed
EP-3039080-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DUPONT TORAY SPECIALTY MATERIALS KK (JP) 2022-05-11 EP disclosed
CN-113214651-A Curable silicone composition, cured product thereof, and optical semiconductor device 杜邦东丽特殊材料株式会社 2021-08-06 CN disclosed
US-10941317-B2 Room-temperature-curable organopolysiloxane composition and base material SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-03-09 US disclosed
US-20200216671-A1 CURABLE SILICONE COMPOSITION, OPTICAL MEMBER RESIN SHEET COMPRISING SAME, AND LIGHT-EMITTING DEVICE DOW TORAY CO., LTD. (JP) 2020-07-09 US disclosed
CN-111278926-A Curable silicone composition, resin sheet for optical member containing same, and light-emitting device 陶氏东丽株式会社 2020-06-12 CN disclosed
CN-105308510-B Silicone rubber composition for heat-conductive silicone-developed rubber member and heat-conductive silicone-developed rubber member 信越化学工业株式会社 2020-05-05 CN disclosed
US-5556829-A AMIDES, SULFONAMIDES, PHOSPHOAMIDES, AGRICULTURAL USE ZAMBON GROUP S.P.A. (IT) 1996-09-17 US disclosed
EP-0709415-A2 Curable base-coat composition, method of film-forming and coated articles NOF CORPORATION (JP) 1996-05-01 EP disclosed
EP-0454067-B1 Compositions having herbicidal activity containing N-Alkyl-amides as active ingredient ZAMBON SPA (IT) 1995-09-27 EP disclosed
EP-0669361-A2 Method for the preparation of polyheterosiloxanes DOW CORNING ASIA, Ltd. (JP) 1995-08-30 EP disclosed
EP-0643112-A2 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORPORATION (JP) 1995-03-15 EP disclosed
US-5336664-A Compositions having herbicidal activity containing N-alkyl-amides as active ingredient ZAMBON GROUP S.P.A. (IT) 1994-08-09 US disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed
US-4739026-A Continuous method for altering the molecular weight of organosilicon compositions WACKER-CHEMIE GMBH (DE) 1988-04-19 US disclosed
EP-0203565-A2 Continuous process for changing the molecular weight of organosilicon compounds Wacker-Chemie GmbH (DE) 1986-12-03 EP disclosed