SCHEMBL465009

SCHEMBL465009

C=C[Si]([O])(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
AKT1 P31749 1/20 0.36
ALOX15 P16050 1/20 0.33
TGM2 P21980 1/20 0.32
CYP2A6 P11509 1/20 0.32
MAPT P10636 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
ADH1B P00325 1/20 0.30
ADH1C P00326 1/20 0.30
ADH1A P07327 1/20 0.30
ADH7 P40394 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3853121 0.79 ALDH1A1 (0.38) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL304128 0.75 MAPT (0.37) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL160241 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL1674781 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL226240 0.72 ALDH1A1 (0.41) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL10795829 0.70 MAPT (0.34) ALDH1A1TSHRAKT1MAPT
SCHEMBL11024215 0.70 ALDH1A1 (0.36) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL11024218 0.69 AKT1 (0.41) ALDH1A1TSHRAKT1ALOX15TGM2
SCHEMBL1566053 0.69 ALDH1A1 (0.34) ALDH1A1TSHRAKT1ALOX15MAPT
SCHEMBL4352107 0.68 TSHR (0.38) ALDH1A1TSHRAKT1ALOX15TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608367-B1 ROOM-TEMPERATURE-CURABLE ORGANOPOLYSILOXANE COMPOSITION AND BASE MATERIAL SHINETSU CHEMICAL CO (JP) 2024-07-10 EP disclosed
US-11981786-B2 Sponge-forming silicone rubber composition and silicone rubber sponge DOW TORAY CO., LTD. (JP) 2024-05-14 US disclosed
US-11981776-B2 Curable silicone composition and cured product thereof, layered product and production method therefor, and optical device or optical display DOW TORAY CO., LTD. (JP) 2024-05-14 US disclosed
WO-2024063070-A1 MULTI-PART SPONGE-FORMING SILICONE RUBBER COMPOSITION ダウ・東レ株式会社 2024-03-28 WO disclosed
WO-2024057924-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, LAYERED BODY, AND OPTICAL DEVICE OR OPTICAL DISPLAY ダウ・東レ株式会社 2024-03-21 WO disclosed
CN-117255836-A Coated article, method of making coated article, and method of making composition 康宁公司 2023-12-19 CN disclosed
US-11780968-B2 Hotmelt silicone composition, encapsulant, hotmelt adhesive and optical semiconductor devise DUPONT TORAY SPECIALTY MATERIALS KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
EP-4186953-A1 ANTI-SULFURIZATION COATING MATERIAL, CURED PRODUCT THEREOF, AND ELECTRONIC DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-31 EP disclosed
US-11634582-B2 Curable white silicone formulation, a reflective material for optical semiconductor module and optical semiconductor device DUPONT TORAY SPECIALTY MATERIALS KABUSHIKI KAISHA (JP) 2023-04-25 US disclosed
US-20230071052-A1 CURABLE SILICONE COMPOSITION, ENCAPSULANT AND OPTICAL SEMICONDUCTOR DEVICE DUROPTIX MATERIALS KABUSHIKI KAISHA (JP) 2023-03-09 US disclosed
US-20070112149-A1 ADDITION CURING SILICONE COMPOSITION FOR CIPG THAT YIELDS CURED PRODUCT WITH EXCELLENT COMPRESSION SET, AND METHOD OF REDUCING COMPRESSION SET OF CURED PRODUCT OF THE COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-05-17 US disclosed
EP-0356075-B1 UV curable siloxane composition containing an adhesion promoter DOW CORNING (US) 1995-09-06 EP disclosed
US-5188864-A A silanetriol containing compound DOW CORNING CORPORATION (US) 1993-02-23 US disclosed
US-5169879-A Storage stable one-package; mercapto functional crosslinker, stabilizers; coatings for optical fibers DOW CORNING CORPORATION (US) 1992-12-08 US disclosed
US-5162389-A Fast ultraviolet radiation curing silicone composition having a high refractive index DOW CORNING CORPORATION (US) 1992-11-10 US disclosed
US-5124212-A Coatings for optical fibers DOW CORNING CORPORATION (US) 1992-06-23 US disclosed
US-4946874-A ONE-PACKAGE MERCAPTO CROSSLINKER DOW CORNING CORPORATION (US) 1990-08-07 US disclosed
US-4923754-A PRIMARY COATING FOR OPTICAL FIBERS DOW CORNING CORPORATION (US) 1990-05-08 US disclosed
US-4921880-A Adhesion promoter for UV curable siloxane compositions and compositions containing same DOW CORNING CORPORATION (US) 1990-05-01 US disclosed
US-4780486-A MERCAPTO CROSSLINKING DOW CORNING CORPORATION (US) 1988-10-25 US disclosed