Sugi Predict

Sugi Predict / Compounds / SCHEMBL46502

SCHEMBL46502

SCHEMBL46502

OCc1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.61
▸ ATM Q13315 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ VHL P40337 1/20 0.50
▸ ELOC Q15369 1/20 0.50
▸ ELOB Q15370 1/20 0.50
▸ PTPN1 P18031 2/20 0.48
▸ TSHR P16473 1/20 0.46
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ LTA4H P09960 1/20 0.41
▸ CYP19A1 P11511 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ MAPK8 P45983 2/20 0.40
▸ MAPK9 P45984 1/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ F2 P00734 1/20 0.40
▸ F10 P00742 1/20 0.40
▸ PRSS1 P07477 1/20 0.40
▸ BACE1 P56817 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067479 0.86 KDM4E (0.55) KDM4EATML3MBTL1VHLELOC
SCHEMBL13141837 0.85 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL13141928 0.85 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL4570432 0.85 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL4570435 0.85 L3MBTL1 (0.64) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL3787566 0.84 KDM4E (0.48) KDM4EATML3MBTL1VHLELOC
SCHEMBL1201083 0.84 KDM4E (0.48) KDM4EATML3MBTL1VHLELOC
SCHEMBL29462713 0.84 L3MBTL1 (0.84) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL77361 0.84 L3MBTL1 (0.84) KDM4EATML3MBTL1PTPN1CYP1A2
SCHEMBL31397606 0.84 L3MBTL1 (0.84) KDM4EATML3MBTL1PTPN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108409635-B Carbazole fluorescent thymine drug labeling reagent, synthesis and application 曲阜师范大学 2021-06-18 — — CN claimed
CN-108409634-B Carbazole fluorescamine compound labeling reagent, synthesis and application 曲阜师范大学 2021-04-27 — — CN claimed
CN-105237774-B A kind of electrochromic material of carbazolyl-containing polyphosphazene and its preparation method and application 黑龙江大学 2018-01-23 — — CN claimed
CN-105237774-A Carbazolylpolyphosphazene-containing electrochromic material, and preparation method and application thereof UNIV HEILONGJIANG 2016-01-13 — — CN claimed
CN-108409635-B Carbazole fluorescent thymine drug labeling reagent, synthesis and application 曲阜师范大学 2021-06-18 — — CN disclosed
CN-108409634-B Carbazole fluorescamine compound labeling reagent, synthesis and application 曲阜师范大学 2021-04-27 — — CN disclosed
CN-108409634-B Carbazole fluorescamine compound labeling reagent, synthesis and application 曲阜师范大学 2021-04-27 — — CN disclosed
EP-2776515-B1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-08-28 — — EP disclosed
CN-105237774-B A kind of electrochromic material of carbazolyl-containing polyphosphazene and its preparation method and application 黑龙江大学 2018-01-23 — — CN disclosed
US-9598450-B2 Emissive compounds for organic light-emitting diodes NITTO DENKO CORPORATION (JP) 2017-03-21 — — US disclosed
US-9598450-B2 Emissive compounds for organic light-emitting diodes NITTO DENKO CORPORATION (JP) 2017-03-21 — — US disclosed
WO-2017007213-A2 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 엘지화학 2017-01-12 — — WO disclosed
US-20090043109-A1 ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE SENSOPATH TECHNOLOGIES, INC. 2009-02-12 — — US disclosed
US-4271187-A Substituted phenyl alanine antihypertensive agents MERCK & CO., INC. (US) 1981-06-02 — — US disclosed
US-4206216-A Antihypertensive N-heterocyclicalanines MERCK & CO., INC. (US) 1980-06-03 — — US disclosed
US-4170654-A Antihypertensive compositions containing N-heterocyclicalanines and α- MERCK & CO., INC. (US) 1979-10-09 — — US disclosed
US-4160835-A Antihypertensive compositions containing an arylsubstituted alanine and a phenyl hydrazinopropionic acid MERCK & CO., INC. (US) 1979-07-10 — — US disclosed
US-4156734-A Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid MERCK & CO., INC. (US) 1979-05-29 — — US disclosed
US-4153715-A Indolyl amino acids useful as antihypertensive agents MERCK & CO., INC. (US) 1979-05-08 — — US disclosed
US-4065572-A Amino acids and esters thereof useful as antihypertensive agents MERCK & CO., INC. (US) 1977-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090043109-A1 ASYMMETRIC ONE- AND TWO-PHOTON FLUOROPHORES FOR SIMULTANEOUS DETECTION OF MULTIPLE ANALYTES USING A COMMON EXCITATION SOURCE ALDH1B1, ALDH2, ALDH3A1 KDM4E 3911/4885ATM 1530/4885L3MBTL1 1585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.