Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL29583964 | 0.91 | IDO1 (0.33) | PDE2AIDO1 | |
| SCHEMBL41567 | 0.82 | CES2 (0.44) | PDE2AIDO1CES2CYP3A4TSHR | |
| SCHEMBL29853969 | 0.82 | PDE2A (0.36) | PDE2AIDO1CES2CTSSCTSK | |
| SCHEMBL30509222 | 0.81 | CES2 (0.39) | PDE2AIDO1CES2TSHRMAPT | |
| SCHEMBL3464534 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR | |
| SCHEMBL6866090 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR | |
| SCHEMBL8004410 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR | |
| SCHEMBL5460964 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL4954250 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR | |
| SCHEMBL226082 | 0.80 | CES2 (0.42) | PDE2AIDO1CES2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577314-B1 | Catalyst based on a transition metal complex for polymerization of olefins, and process for polymerization of olefins using the catalyst | TOSOH CORP (JP) | 2008-08-27 | — | — | EP | disclosed |
| EP-1392740-B1 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS WITH A BIS-AMIDO TITANIUM COMPOUND | BASELL POLYOLEFINE GMBH (DE) | 2008-08-20 | — | — | EP | disclosed |
| US-7202315-B2 | Process for the preparation of ethylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2007-04-10 | — | — | US | disclosed |
| US-7153916-B2 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of ofelin using the catalyst | TOSOH CORPORATION (JP) | 2006-12-26 | — | — | US | disclosed |
| EP-1577314-A1 | Catalyst based on a transition metal complex for polymerization of olefin, and process for polymerization of olefin using the catalyst | Tosoh Corporation (JP) | 2005-09-21 | — | — | EP | disclosed |
| EP-1241175-B1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORP (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6919292-B2 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20040097668-A1 | Process for the preparation of ethylene polymers | SANTAN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-20 | — | — | US | disclosed |
| US-20030018145-A1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-1241175-A2 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | Tosoh Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-6372684-B1 | COORDINATION CATALYSTS COMPRISING ZIRCONIUM, TITANIUM, OR HAFNIUM METAL COMPLEX WITH BIS-AMIDO COMPOUND; BORON COMPOUND COCATALYST; AND ORGANOALUMINUM COMPOUNDS; ADDITION POLYMERIZATION; CATALYST SELECTIVITY | SHELL OIL COMPANY | 2002-04-16 | — | — | US | disclosed |
| US-20020035219-A1 | Catalyst system for alpha-olefin oligomerization | HORTON ANDREW D (NL) | 2002-03-21 | — | — | US | disclosed |
| EP-1073521-A1 | CATALYST SYSTEM FOR ALPHA-OLEFIN OLIGOMERIZATION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999052631-A1 | CATALYST SYSTEM FOR α-OLEFIN OLIGOMERIZATION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1999-10-21 | — | — | WO | disclosed |
| US-5561216-A | PROVIDES CONTROLLED MOLECULAR WEIGHT AND NARROW MOLECULAR WEIGHT DISTRIBUTION | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-10-01 | — | — | US | disclosed |
| US-5516739-A | NICKEL OR PALLADIUM COMPLEXES; ETHYLENE-CARBON MONOXIDE COPOLYMERS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018145-A1 | Transition metal compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | PORCN, OSTC, PPOX | PDE2A 4883/4885IDO1 1959/4885CES2 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.