Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424329 | 1.00 | KDM4E (0.42) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL223751 | 0.81 | ALDH1A1 (0.50) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL454277 | 0.70 | HTR2A (0.43) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL4127395 | 0.70 | KDM4E (0.42) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL2072294 | 0.70 | KDM4E (0.50) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL4437258 | 0.69 | ALDH1A1 (0.40) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL21668867 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL3925948 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL7078918 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1GPR3HSD17B10HTR2A | |
| SCHEMBL27741230 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241543-A | Polycyclic nitrogen heterocyclic compound and preparation method thereof | 中国科学院成都生物研究所 | 2025-01-03 | — | — | CN | claimed |
| CN-118146220-A | Method for synthesizing dihydro-beta-carboline by oxidative dehydrogenation of tetrahydro-beta-carboline | 西安石油大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116287050-A | Imine reductase, mutant and application thereof in synthesis of tetrahydro-beta-carboline derivatives | 复旦大学 | 2023-06-23 | — | — | CN | claimed |
| CN-104744460-B | β carbolines, dihydro β carbolines and tetrahydro-beta-carboline alcaloid-derivatives and preparation method thereof and the application in terms of preventing and treating plant virus, sterilization, desinsection | 南开大学 | 2017-06-16 | — | — | CN | claimed |
| US-20160326166-A1 | ß-CARBOLINE, DIHYDRO-ß-CARBOLINE AND TETRAHYDRO-ß-CARBOLINE ALKALOID DERIVATIVES AND PREPARATION METHODS SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, FUNGICIDES AND INSECTICIDES | NANKAI UNIVERSITY (CN) | 2016-11-10 | — | — | US | claimed |
| EP-3091015-A1 | BETA-CARBOLINE, DIHYDRO-BETA-CARBOLINE AND TETRAHYDRO-BETA-CARBOLINE ALKALOID DERIVATIVES AND METHOD FOR PREPARING SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, FUNGICIDES AND INSECTICIDES | Nankai University (CN) | 2016-11-09 | — | — | EP | claimed |
| CN-104744460-A | B-carboline, dihydro-B-carboline and tetrahydro-B-carboline alkaloid derivative as well as preparation method and application in aspects of plant virus prevention and cure, sterilization and insecticide | UNIV NANKAI | 2015-07-01 | — | — | CN | claimed |
| EP-0251194-B1 | USE OF CARBOCYCLIC AND HETEROCYCLIC CONDENSED DIHYDROPYRIDINES FOR THE PREPARATION OF CARDIOPROTECTIVE REMEDIES AND HETEROCYCLIC AND CARBOCYCLIC CONDENSED DIHYDROPYRIDINES AND METHODS AND INTERMEDIATES FOR THEIR PREPARATION | BOEHRINGER INGELHEIM KG (DE) | 1993-03-31 | — | — | EP | claimed |
| EP-0251194-A1 | Use of carbocyclic and heterocyclic condensed dihydropyridines for the preparation of cardioprotective remedies and heterocyclic and carbocyclic condensed dihydropyridines and methods and intermediates for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-07 | — | — | EP | claimed |
| CN-119241543-A | Polycyclic nitrogen heterocyclic compound and preparation method thereof | 中国科学院成都生物研究所 | 2025-01-03 | — | — | CN | disclosed |
| CN-119241543-A | Polycyclic nitrogen heterocyclic compound and preparation method thereof | 中国科学院成都生物研究所 | 2025-01-03 | — | — | CN | disclosed |
| CN-118146220-A | Method for synthesizing dihydro-beta-carboline by oxidative dehydrogenation of tetrahydro-beta-carboline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118146220-A | Method for synthesizing dihydro-beta-carboline by oxidative dehydrogenation of tetrahydro-beta-carboline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-118146220-A | Method for synthesizing dihydro-beta-carboline by oxidative dehydrogenation of tetrahydro-beta-carboline | 西安石油大学 | 2024-06-07 | — | — | CN | disclosed |
| EP-0559838-A4 | ECTEINASCIDINS 736 AND 722 | UNIV ILLINOIS (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0559838-A1 | ECTEINASCIDINS 736 AND 722. | UNIV ILLINOIS (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0251194-B1 | USE OF CARBOCYCLIC AND HETEROCYCLIC CONDENSED DIHYDROPYRIDINES FOR THE PREPARATION OF CARDIOPROTECTIVE REMEDIES AND HETEROCYCLIC AND CARBOCYCLIC CONDENSED DIHYDROPYRIDINES AND METHODS AND INTERMEDIATES FOR THEIR PREPARATION | BOEHRINGER INGELHEIM KG (DE) | 1993-03-31 | — | — | EP | disclosed |
| US-5149804-A | Antitumor agent | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1992009607-A1 | ECTEINASCIDINS 736 AND 722 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0251194-A1 | Use of carbocyclic and heterocyclic condensed dihydropyridines for the preparation of cardioprotective remedies and heterocyclic and carbocyclic condensed dihydropyridines and methods and intermediates for their preparation | BOEHRINGER INGELHEIM KG (DE) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326166-A1 | ß-CARBOLINE, DIHYDRO-ß-CARBOLINE AND TETRAHYDRO-ß-CARBOLINE ALKALOID DERIVATIVES AND PREPARATION METHODS SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, FUNGICIDES AND INSECTICIDES | DDT, NOTUM, DDAH1 | KDM4E 1695/4885NR2E1 2422/4885HTR5A 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.