Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL465036 | 1.00 | KDM4E (0.42) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL223751 | 0.81 | ALDH1A1 (0.50) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL454277 | 0.70 | HTR2A (0.43) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL4127395 | 0.70 | KDM4E (0.42) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL2072294 | 0.70 | KDM4E (0.50) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL4437258 | 0.69 | ALDH1A1 (0.40) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL21668867 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL3925948 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 | |
| SCHEMBL7078918 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1GPR3HSD17B10HTR2A | |
| SCHEMBL27741230 | 0.69 | KDM4E (0.41) | KDM4ENR2E1HTR5ANISCHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915987-B1 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSTEOQC INC (CA) | 2023-12-13 | — | — | EP | disclosed |
| CN-113462662-B | Enzyme for preparing chiral tetrahydro beta-carboline and preparation method and application thereof | 上海交通大学 | 2022-11-11 | — | — | CN | disclosed |
| US-11267814-B2 | Compounds for bone growth | OsteoQC, Inc. | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11267814-B2 | Compounds for bone growth | FGF1, FGF2, BMP2 | KDM4E 2795/4885NR2E1 1184/4885HTR5A 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.