SCHEMBL9753036

SCHEMBL9753036

COc1cc(OC)c(N)c(S(=O)(=O)O)c1.COc1cc(S(=O)(=O)O)c(OC)cc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.54
ALDH1A1 P00352 5/20 0.39
CYP3A4 P08684 3/20 0.39
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 2/20 0.36
THRB P10828 2/20 0.36
KDM4E B2RXH2 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
APEX1 P27695 1/20 0.36
MAPK1 P28482 1/20 0.36
BRCA1 P38398 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
SLC10A1 Q14973 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8064211 0.89 ERN1 (0.42) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4650366 0.86 PKM (0.70) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4649818 0.80 PKM (0.59) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL1755131 0.76 PKM (0.55) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL8568415 0.76 PKM (0.55) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL4649757 0.76 PKM (0.59) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL8113725 0.76 PKM (0.59) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL1888725 0.76 ALDH1A1 (0.51) PKMALDH1A1MAPTKMT2ALMNA
SCHEMBL2914715 0.74 PKM (0.56) PKMALDH1A1CYP3A4MAPTKMT2A
SCHEMBL9233010 0.73 PKM (0.51) PKMALDH1A1CYP3A4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO disclosed