Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934440 | 0.89 | EIF4E (0.44) | CASP1KMT2ACHRM3ATMMKNK1 | |
| SCHEMBL5616409 | 0.88 | CASP1 (0.55) | CASP1KMT2AMEN1ALDH1A1CHRM3 | |
| SCHEMBL22320212 | 0.86 | IDO1 (0.44) | CASP1ALOX5APFEN1CES2CES1 | |
| SCHEMBL3904946 | 0.83 | ALOX5AP (0.56) | CASP1ALOX5APFEN1KMOKMT2A | |
| SCHEMBL5616523 | 0.83 | CASP1 (0.46) | CASP1KDM4EALDH1A1MAPK14IKBKB | |
| SCHEMBL5616614 | 0.82 | IKBKB (0.51) | CES2CES1KMT2AMEN1DGAT1 | |
| SCHEMBL4650415 | 0.82 | AKR1C3 (0.45) | ALOX5APFEN1KMOCES2CES1 | |
| SCHEMBL20573272 | 0.78 | BCL9 (0.44) | KMOCHRM3 | |
| SCHEMBL28142061 | 0.78 | IKBKB (0.48) | CES2CES1KMT2AMEN1DGAT1 | |
| SCHEMBL4615110 | 0.77 | EIF4E (0.47) | CASP1EIF4EPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856054-B1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1856054-A1 | PYRAZOLYLCARBOXANILIDES | Bayer CropScience AG (DE) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092213-A1 | PYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-08 | — | — | WO | disclosed |