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SCHEMBL2934440

SCHEMBL2934440

NC(=O)c1ccc(F)cc1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EIF4E P06730 6/20 0.44
▸ PSEN1 P49768 2/20 0.43
▸ PSEN2 P49810 2/20 0.43
▸ APH1B Q8WW43 2/20 0.43
▸ NCSTN Q92542 2/20 0.43
▸ APH1A Q96BI3 2/20 0.43
▸ PSENEN Q9NZ42 2/20 0.43
▸ APP P05067 2/20 0.43
▸ CASP1 P29466 1/20 0.43
▸ SCN9A Q15858 1/20 0.42
▸ AHR P35869 3/20 0.42
▸ CHRM2 P08172 2/20 0.41
▸ CHRM1 P11229 2/20 0.41
▸ CHRM3 P20309 2/20 0.41
▸ MKNK1 Q9BUB5 1/20 0.41
▸ MKNK2 Q9HBH9 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4650433 0.89 CASP1 (0.42) EIF4ECASP1CHRM3MKNK1MKNK2
SCHEMBL5616409 0.89 CASP1 (0.55) CASP1CHRM2CHRM1CHRM3MKNK1
SCHEMBL4615110 0.88 EIF4E (0.47) EIF4EPSEN1PSEN2APH1BNCSTN
SCHEMBL5616523 0.84 CASP1 (0.46) CASP1SCN9A
SCHEMBL5616614 0.83 IKBKB (0.51) MKNK2CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL22320212 0.81 IDO1 (0.44) CASP1AKR1C3AKR1C2KMT2A
SCHEMBL3234101 0.79 BCAT2 (0.59) EIF4ECASP1AHRCHRM1MKNK1
SCHEMBL28142061 0.79 IKBKB (0.48) CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL20573251 0.78 CHRM3 (0.42) EIF4EPSEN1PSEN2APH1BNCSTN
SCHEMBL16416508 0.78 GCGR (0.45) EIF4EPSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230113346-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2023-04-13 — — US claimed
US-20150366201-A1 FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE SYNGENTA PARTICIPATIONS AG (CH) 2015-12-24 — — US claimed
US-20150181877-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2015-07-02 — — US claimed
EP-2877025-A1 FUNGICIDAL COMPOSITIONS Syngenta Participations AG (CH) 2015-06-03 — — EP claimed
WO-2014016279-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2014-01-30 — — WO claimed
US-20130217745-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2013-08-22 — — US claimed
WO-2013011010-A1 FUNGIZIDE MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2013-01-24 — — WO claimed
WO-2012069652-A2 FUNGICIDE MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-05-31 — — WO claimed
US-20100216640-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-08-26 — — US claimed
EP-2150113-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2010-02-10 — — EP claimed
WO-2008131901-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2008-11-06 — — WO claimed
US-11647749-B2 Fungicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2023-05-16 — — US disclosed
US-20230113346-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2023-04-13 — — US disclosed
US-11570990-B2 Fungicidal compositions comprising 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid methoxy-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-amide and an azole SYNGENTA PARTICIPATIONS AG (CH) 2023-02-07 — — US disclosed
CN-106614620-B Fungicidal compositions 先正达参股股份有限公司 2022-07-15 — — CN disclosed
EP-2150113-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2010-02-10 — — EP disclosed
WO-2009135860-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2009-11-12 — — WO disclosed
WO-2009090038-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2009-07-23 — — WO disclosed
WO-2008131901-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2008-11-06 — — WO disclosed
WO-2007071656-A1 METHOD FOR CONTROLLING RUSTING IN LEGUMINOUS PLANTS BASF AKTIENGESELLSCHAFT (DE) 2007-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647749-B2 Fungicidal compositions BROX, RER1, BLVRB EIF4E 2518/4885PSEN1 226/4885PSEN2 679/4885
US-20150366201-A1 FUNGICIDAL COMPOSITIONS COMPRISING A CARBOXAMIDE CBR3, CBR1, C9 EIF4E 2724/4885PSEN1 2415/4885PSEN2 3408/4885
US-20100216640-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB EIF4E 2140/4885PSEN1 243/4885PSEN2 630/4885
US-20150181877-A1 FUNGICIDAL COMPOSITIONS CYP51A1, ERG28, DPM1 EIF4E 3311/4885PSEN1 781/4885PSEN2 956/4885
US-20230113346-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB EIF4E 2518/4885PSEN1 226/4885PSEN2 679/4885
US-20130217745-A1 FUNGICIDAL COMPOSITIONS CBR3, C1S, C9 EIF4E 2859/4885PSEN1 1226/4885PSEN2 2137/4885
US-11570990-B2 Fungicidal compositions comprising 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid methoxy-[1-methyl-2-(2,4,6-trichlorophenyl)-ethyl]-amide and an azole CBR3, TH, CBR1 EIF4E 1964/4885PSEN1 2921/4885PSEN2 3597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.