SCHEMBL29465675

SCHEMBL29465675

O=C(O)c1ccc(N=Nc2ccc(C(=O)O)cc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.58
CD69 Q07108 1/20 0.56
EGFR P00533 1/20 0.55
GLO1 Q04760 2/20 0.54
RPS6KA3 P51812 1/20 0.54
MAPT P10636 9/20 0.52
POLB P06746 7/20 0.52
GAA P10253 4/20 0.52
KDM4E B2RXH2 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 2/20 0.52
CA6 P23280 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
PTGS2 P35354 1/20 0.52
KMT2A Q03164 9/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740933 0.91 TRPA1 (0.61) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL4650520 0.91 TRPA1 (0.61) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL9987224 0.91 CA12 (0.61) TRPA1EGFRGLO1MAPTPOLB
SCHEMBL1803799 0.88 HDAC6 (0.47) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL12620637 0.88 HDAC6 (0.47) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL1811198 0.86 RAB9A (0.60) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL1811197 0.86 RAB9A (0.60) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL21466069 0.85 CD69 (0.46) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL21242738 0.85 SIRT5 (0.44) TRPA1CD69EGFRGLO1RPS6KA3
SCHEMBL26156357 0.83 ALDH1A1 (0.53) TRPA1CD69EGFRGLO1RPS6KA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058361-A Preparation method of organogel with photochromism and fluorescence 江南大学 2022-02-18 CN disclosed