Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970697 | 0.85 | MCL1 (0.58) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| Hydrochloric Acid SCHEMBL27544067 | 0.83 | MCL1 (0.56) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL8631381 | 0.74 | OGG1 (0.43) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL8904180 | 0.74 | CYP2A6 (0.47) | MCL1HDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL64428 | 0.72 | MCL1 (0.73) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL2721044 | 0.68 | MCL1 (0.49) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL27629193 | 0.68 | MCL1 (0.53) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL30980091 | 0.67 | PTGS2 (0.56) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL2610245 | 0.67 | RXFP1 (0.59) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL11147963 | 0.66 | ALDH1A1 (0.44) | MCL1HDAC1HDAC8HDAC6OGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |