Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.66 |
| ▸ | RELA | Q04206 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579796 | 0.90 | MAPK1 (0.75) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8930036 | 0.82 | MAPK1 (0.82) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4650780 | 0.81 | MAPK1 (0.79) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4652064 | 0.78 | MAPK1 (0.75) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| Fenfuram SCHEMBL18978 | 0.76 | SMN1; SMN2 (0.73) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL13645619 | 0.75 | MAPK1 (0.69) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14579829 | 0.74 | MAPK1 (0.68) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3149525 | 0.73 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1GAA | |
| SCHEMBL14041225 | 0.73 | MAPK1 (0.61) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL14579830 | 0.73 | MAPK1 (0.66) | MAPK1ESR2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513824-B1 | FURANCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-01 | — | — | EP | disclosed |
| US-7179840-B2 | Furancarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179840-B2 | Furancarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179840-B2 | Furancarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-20060142381-A1 | Furancarboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-06-29 | — | — | US | disclosed |
| EP-1513824-A1 | FURANCARBOXAMIDES | Bayer CropScience AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099803-A1 | FURANCARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142381-A1 | Furancarboxamides | DDT, MRM1, FPR1 | MAPK1 3713/4885ESR2 2380/4885RAB9A 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.