Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645618 | 0.81 | KMT2A (0.49) | MAPK1ESR2MEN1KMT2A | |
| SCHEMBL3863550 | 0.80 | SMN1; SMN2 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8930036 | 0.77 | MAPK1 (0.82) | MAPK1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL13645650 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13292708 | 0.77 | ALDH1A1 (0.44) | MAPK1ESR2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4650780 | 0.76 | MAPK1 (0.79) | MAPK1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL13645568 | 0.76 | ATM (0.48) | MAPK1ESR2ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL12995254 | 0.76 | TDP1 (0.55) | ALDH1A1NPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4650804 | 0.75 | MAPK1 (0.77) | MAPK1ESR2ALDH1A1NPC1RAB9A | |
| SCHEMBL13645570 | 0.74 | KMT2A (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598389-B2 | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191454-A1 | Silylated carboxamides | MRPL21, MRPS22, MRPS34 | MAPK1 3872/4885ESR2 1886/4885ALDH1A1 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.