Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 17/20 | 0.53 |
| ▸ | PLK3 | Q9H4B4 | 5/20 | 0.53 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650811 | 0.84 | PLK1 (0.53) | PLK1PLK3SLC16A3PTPN2PTPN1 | |
| SCHEMBL4652862 | 0.82 | GPR35 (0.47) | PLK1PLK3 | |
| SCHEMBL4651959 | 0.75 | PLK1 (0.61) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL4651952 | 0.75 | PLK1 (0.61) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL4650949 | 0.75 | PLK1 (0.61) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL4651560 | 0.74 | MAPT (0.40) | — | |
| SCHEMBL4651954 | 0.70 | PLK1 (0.60) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL4650948 | 0.70 | PLK1 (0.60) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL4651949 | 0.70 | PLK1 (0.60) | PLK1PLK3PTPN2PTPN1PTPN6 | |
| SCHEMBL28808948 | 0.69 | PLK1 (0.97) | PLK1PLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |