Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.41 |
| ▸ | THRA | P10827 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652552 | 0.87 | THRB (0.40) | THRBTHRAL3MBTL1MEN1KMT2A | |
| SCHEMBL4650582 | 0.80 | ALDH1A1 (0.49) | THRBTHRAL3MBTL1MEN1KMT2A | |
| SCHEMBL4650517 | 0.80 | ALDH1A1 (0.44) | THRAL3MBTL1 | |
| SCHEMBL17970243 | 0.77 | THRB (0.47) | THRBTHRAMEN1KMT2ACYP4A11 | |
| SCHEMBL15825227 | 0.76 | PPARG (0.42) | THRBTHRAPPARGCYP4A11CYP4F2 | |
| SCHEMBL3687860 | 0.75 | PLK1 (0.41) | THRBTHRAL3MBTL1KMT2ACYP4A11 | |
| SCHEMBL13706560 | 0.75 | FKBP1A (0.39) | THRBTHRAPPARGCYP4A11 | |
| SCHEMBL10648871 | 0.75 | THRB (0.45) | THRBTHRAL3MBTL1MEN1KMT2A | |
| SCHEMBL195630 | 0.75 | RARB (0.57) | THRBTHRAMEN1KMT2AHSD17B10 | |
| SCHEMBL9808693 | 0.75 | CYP4A11 (0.57) | THRBTHRACYP4A11CYP4F2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072326-B1 | Surface active photoinitiator | CIBA HOLDING INC (CH) | 2008-09-17 | — | — | EP | disclosed |
| US-6693141-B2 | PHOTOCURABLE UNSATURATED MONOMER AND OPTIONALLY HEAT CURABLE MONOMER; PHOTOINITIATOR IS PREFERABLY A SILOXANE OLIGOMER CONTAINING A BENZOYL GROUP | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-02-17 | — | — | US | disclosed |
| US-20020107297-A1 | Surface-active photoinitiators | IGM GROUP B.V. (NL) | 2002-08-08 | — | — | US | disclosed |
| US-6376568-B1 | MODIFIED POLYSILOXANE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-23 | — | — | US | disclosed |
| EP-1072326-A2 | Surface active photoinitiator | Ciba SC Holding AG (CH) | 2001-01-31 | — | — | EP | disclosed |