Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071630 | 0.85 | KLK5 (0.43) | KLK5TACR1SCN9ACYP1A2CYP2C9 | |
| SCHEMBL12035787 | 0.84 | MTNR1A (0.46) | KLK5TACR1SCN9ACTSSCTSK | |
| SCHEMBL13352198 | 0.84 | MTNR1A (0.46) | KLK5TACR1SCN9ACTSSCTSK | |
| SCHEMBL17061439 | 0.84 | MTNR1A (0.46) | KLK5TACR1SCN9ACTSSCTSK | |
| SCHEMBL8932203 | 0.78 | SCN9A (0.35) | TACR1SCN9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29361110 | 0.77 | SCN9A (0.50) | TACR1SCN9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL584547 | 0.76 | SCN9A (0.49) | KLK5TACR1SCN9ACYP1A2CYP2C9 | |
| SCHEMBL15711996 | 0.75 | KLK5 (0.49) | KLK5TACR1CTSSCTSKEPHX2 | |
| SCHEMBL8008614 | 0.75 | KLK5 (0.49) | KLK5TACR1CTSSCTSKEPHX2 | |
| SCHEMBL1571749 | 0.74 | SCN9A (0.47) | KLK5TACR1SCN9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150252067-A1 | NICKEL FLUORINATING COMPLEXES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-09-10 | — | — | US | disclosed |
| EP-1697279-B1 | RADICAL TRAP IN FLUORIDATION OF IODINIUM SALT | GE HEALTHCARE LTD (GB) | 2008-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252067-A1 | NICKEL FLUORINATING COMPLEXES AND USES THEREOF | SLC39A3, SLC39A14, SLC39A7 | KLK5 1713/4885TACR1 1930/4885SCN9A 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.