Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 9/20 | 0.52 |
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147709 | 0.89 | NPY1R (0.45) | F7KLKB1NPFFR1NPFFR2NPY1R | |
| SCHEMBL7058205 | 0.89 | NPY1R (0.57) | F7F2F10PRSS1TMPRSS6 | |
| SCHEMBL7798487 | 0.89 | NPY1R (0.57) | F7F2F10PRSS1TMPRSS6 | |
| SCHEMBL8112148 | 0.85 | F2 (0.52) | F7F2F10PRSS1TMPRSS6 | |
| SCHEMBL8121755 | 0.82 | CTSB (0.46) | KLKB1ANPEPCTSL | |
| SCHEMBL8121714 | 0.81 | NPY1R (0.59) | NPFFR1NPFFR2NPY1RNPY5RCTSL | |
| SCHEMBL8526149 | 0.80 | F2 (0.54) | F7F2F10PRSS1TMPRSS6 | |
| SCHEMBL7802954 | 0.78 | NPY1R (0.61) | F7F2TMPRSS6NPFFR1NPFFR2 | |
| SCHEMBL7802851 | 0.78 | F2 (0.54) | F7F2F10PRSS1TMPRSS6 | |
| SCHEMBL8121971 | 0.77 | NPY1R (0.58) | NPFFR1NPFFR2NPY1RNPY5RCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007077333-A2 | USE OF A NEUROPEPTIDE Y ANTAGONIST FOR DAMAGED OR SENSITIVE LIPS | L'OREAL (FR) | 2007-07-12 | — | — | WO | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |