Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121971 | 0.89 | NPY1R (0.58) | NPY1RNPFFR1NPFFR2NPY5RCTSL | |
| SCHEMBL4652020 | 0.89 | F7 (0.54) | NPY1RNPFFR1NPFFR2NPY5RF7 | |
| SCHEMBL8127200 | 0.88 | CTSB (0.39) | F7KLKB1ANPEPCTSLMMP1 | |
| SCHEMBL8121755 | 0.82 | CTSB (0.46) | KLKB1ANPEPCTSLMMP1FCER2 | |
| SCHEMBL7041564 | 0.79 | CTSB (0.48) | NPY1RNPFFR1NPFFR2NPY5RKLKB1 | |
| SCHEMBL8121714 | 0.79 | NPY1R (0.59) | NPY1RNPFFR1NPFFR2NPY5RCTSL | |
| SCHEMBL7798487 | 0.77 | NPY1R (0.57) | NPY1RNPFFR1NPFFR2NPY5RF7 | |
| SCHEMBL7058205 | 0.77 | NPY1R (0.57) | NPY1RNPFFR1NPFFR2NPY5RF7 | |
| SCHEMBL8112148 | 0.74 | F2 (0.52) | NPY1RNPFFR1NPFFR2NPY5RF7 | |
| SCHEMBL11780493 | 0.72 | CTSL (0.73) | KLKB1ANPEPCTSLMMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |