Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 2/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL5719481 | 0.90 | ITGB3 (0.67) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL219151 | 0.88 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL26661077 | 0.88 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL479010 | 0.88 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL7372270 | 0.88 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL220648 | 0.88 | TACR1 (0.68) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| Glycine SCHEMBL7320734 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| Glycine SCHEMBL7316336 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| Hypochlorous Acid SCHEMBL7368156 | 0.85 | TACR1 (0.65) | ITGB3ITGA2BALDH1A1ALOX15CTSL | |
| SCHEMBL2576567 | 0.84 | ALDH1A1 (0.65) | ITGB3ITGA2BALDH1A1ALOX15CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408986-B1 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2008-09-24 | — | — | EP | disclosed |
| US-7312246-B2 | Proteomimetic compounds and methods | YALE UNIVERSITY (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1408986-A4 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2006-01-11 | — | — | EP | disclosed |
| US-20050215563-A1 | Proteomimetic compounds and methods | YALE UNIVERSITY | 2005-09-29 | — | — | US | disclosed |
| US-6858600-B2 | Proteomimetic compounds and methods | YALE UNIVERSITY (US) | 2005-02-22 | — | — | US | disclosed |
| EP-1408986-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20030008882-A1 | Proteomimetic compounds and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | disclosed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008882-A1 | Proteomimetic compounds and methods | PACSIN2, HSP90B1, PHLPP2 | ITGB3 3716/4885ITGA2B 3962/4885ALDH1A1 4826/4885 |
| US-20050215563-A1 | Proteomimetic compounds and methods | PACSIN2, HSP90B1, PHLPP2 | ITGB3 3716/4885ITGA2B 3962/4885ALDH1A1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.