SCHEMBL465226

SCHEMBL465226

CCCC(=O)ON1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
TSHR P16473 2/20 0.45
POLB P06746 2/20 0.45
ALDH1A1 P00352 5/20 0.44
RAB9A P51151 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
GLA P06280 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RECQL P46063 1/20 0.40
HTT P42858 2/20 0.39
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27723070 0.98 LMNA (0.44) LMNATSHRPOLBALDH1A1RAB9A
Propionic Acid SCHEMBL10343203 0.93 ALDH1A1 (0.41) LMNATSHRPOLBALDH1A1RAB9A
SCHEMBL8526268 0.89 RAB9A (0.46) LMNATSHRPOLBALDH1A1RAB9A
SCHEMBL1194369 0.88 TSHR (0.46) LMNATSHRPOLBALDH1A1RAB9A
SCHEMBL324052 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1
SCHEMBL323833 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1
SCHEMBL324921 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1
SCHEMBL11650239 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1
SCHEMBL21603056 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1
SCHEMBL7158840 0.86 LMNA (0.47) LMNAPOLBALDH1A1RAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1637141-B1 Stabilized protease composition comprising a serine protease, morpholino derivatives and reversible inhibitors of said serine protease TROBIO AB (SE) 2011-11-16 EP claimed
WO-2011131234-A1 SENSOR APPARATUS ADAPTED TO BE INCORPORATED IN A GARMENT WEARABLE INFORMATION TECHNOLOGIES, S.L. (WEARTECH) (ES) 2011-10-27 WO claimed
US-20090136474-A1 Stabilized Protease Composition TROBIO AB (SE) 2009-05-28 US claimed
WO-2007035143-A1 STABILIZED PROTEASE COMPOSITION TROBIO AB (SE) 2007-03-29 WO claimed
EP-1637141-A1 Stabilized protease composition comprising a serine protease, morpholino derivatives and reversible inhibitors of said serine protease Trobio AB (SE) 2006-03-22 EP claimed
CN-113321269-A Method for effectively separating organic matters in high-salinity wastewater 中国科学院过程工程研究所 2021-08-31 CN disclosed
CN-104622809-B The drug of modification for elaioplast nanometer particle 英属哥伦比亚大学 2019-04-19 CN disclosed
CN-106132972-A For treating the novel amino phosphate ester of HCV infection 银杏树药业(苏州)有限公司 2016-11-16 CN disclosed
CN-102105135-B Modified drugs for liposomal nanoparticles 英属哥伦比亚大学 2016-08-24 CN disclosed
CN-104622809-A Modified drugs for use in liposomal nanoparticles UNIV BRITISH COLUMBIA 2015-05-20 CN disclosed
US-8574569-B2 Stabilized protease composition TROBIO AB (SE) 2013-11-05 US disclosed
US-20130157339-A1 STABILIZED PROTEASE COMPOSITION TROBIO AB (SE) 2013-06-20 US disclosed
CN-102105135-A Modified drugs for liposomal nanoparticles UNIV BRITISH COLUMBIA 2011-06-22 CN disclosed
CN-101528846-A Inorganic-organic hybrid composition and use thereof NOF CORP (JP) 2009-09-09 CN disclosed
US-20090136474-A1 Stabilized Protease Composition TROBIO AB (SE) 2009-05-28 US disclosed
CN-101384586-A PI-3 kinase inhibitors and methods of use thereof NOVARTIS AG (CH) 2009-03-11 CN disclosed
WO-2007035143-A1 STABILIZED PROTEASE COMPOSITION TROBIO AB (SE) 2007-03-29 WO disclosed
EP-1637141-A1 Stabilized protease composition comprising a serine protease, morpholino derivatives and reversible inhibitors of said serine protease Trobio AB (SE) 2006-03-22 EP disclosed
CN-1299348-A sPLA for treatment of disease2Inhibitor compounds LILLY CO ELI (US) 2001-06-13 CN disclosed
CN-1131420-A Anhydrous crystalline MYCOPHENOLATE 2- (4-morpholino) ethyl ester (MYCOPHENOLATE MOFETIL) and intravenous formulations thereof SYNTEX S A INC (US) 1996-09-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090136474-A1 Stabilized Protease Composition SERPINE1, SERPINB1, CTRL LMNA 505/4885TSHR 4487/4885POLB 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.