Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.45 |
| ▸ | BAD | Q92934 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 8/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254637 | 0.87 | GPR35 (0.62) | GPR35MCL1BCL2L1BCL2BAD | |
| SCHEMBL1254639 | 0.87 | GPR35 (0.62) | GPR35MCL1BCL2L1BCL2BAD | |
| SCHEMBL4651563 | 0.86 | ALDH1A1 (0.46) | GPR35MCL1 | |
| SCHEMBL4650811 | 0.81 | PLK1 (0.53) | PLK1PLK3 | |
| SCHEMBL12430808 | 0.80 | MAPT (0.43) | GPR35PLK1PLK3 | |
| SCHEMBL4652862 | 0.80 | GPR35 (0.47) | GPR35MCL1BCL2L1PLK1LDHA | |
| SCHEMBL3340064 | 0.79 | GPR35 (0.56) | GPR35MCL1BCL2L1BCL2BAD | |
| SCHEMBL6616990 | 0.77 | MCL1 (0.65) | GPR35MCL1BCL2L1BCL2BAD | |
| SCHEMBL9486183 | 0.77 | EIF4A1 (0.47) | GPR35MCL1BCL2L1BCL2BAD | |
| Hydrochloric Acid SCHEMBL9487425 | 0.76 | EIF4A1 (0.46) | GPR35MCL1BCL2L1BCL2BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972624-A1 | Benzoxazinones and their use as ultraviolet light absorbers | Clariant International Ltd. (CH) | 2008-09-24 | — | — | EP | disclosed |