SCHEMBL4653348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4653351	1.00	MEN1 (0.53)	MEN1KMT2APTGS1PTGS2ALDH1A1
	SCHEMBL27838696	0.83	MEN1 (0.64)	MEN1KMT2APTGS1PTGS2ALDH1A1
	SCHEMBL4890340	0.83	ALDH1A1 (0.54)	MEN1KMT2AALDH1A1AKR1C3KDM4E
	SCHEMBL4890342	0.83	ALDH1A1 (0.54)	MEN1KMT2AALDH1A1AKR1C3KDM4E
	SCHEMBL14087904	0.82	AKR1C3 (0.75)	PTGS2AKR1C3
	SCHEMBL14087892	0.80	MTNR1A (0.59)	MEN1KMT2APTGS2ALDH1A1AKR1C3
	SCHEMBL19436967	0.79	TLR9 (0.59)	MEN1KMT2AALDH1A1MAOAMAOB
	SCHEMBL14087896	0.79	MEN1 (0.53)	MEN1KMT2AALDH1A1AKR1C3MAPT
	SCHEMBL19436965	0.79	TLR9 (0.59)	MEN1KMT2AALDH1A1MAOAMAOB
	SCHEMBL3802163	0.78	MEN1 (0.61)	MEN1KMT2APTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.