SCHEMBL465363

SCHEMBL465363

CCC(C)c1cc(C(C)(C)c2ccccc2)ccc1Nc1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.52
NR3C2 P08235 3/20 0.43
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
GAA P10253 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 4/20 0.36
CYP3A4 P08684 3/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
MAP2K1 Q02750 1/20 0.35
TSHR P16473 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
GFER P55789 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465496 0.85 NR3C2 (0.39) RORCNR3C2KDM4EMEN1KMT2A
SCHEMBL2364617 0.80 RORC (0.35) RORCNR3C2KDM4EMEN1KMT2A
SCHEMBL11051907 0.77 RORC (0.58) RORCNR3C2KDM4EMEN1KMT2A
SCHEMBL465362 0.75 MEN1 (0.36) NR3C2KDM4EMEN1KMT2AGAA
SCHEMBL465396 0.75 NR3C2 (0.46) NR3C2KDM4EMEN1KMT2AGAA
SCHEMBL465481 0.74 NR3C2 (0.40) NR3C2KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL11806715 0.74 NR3C2 (0.45) NR3C2KDM4EMEN1KMT2AGAA
SCHEMBL11810264 0.73 TSHR (0.50) KDM4EMEN1KMT2AGAASMN1; SMN2
SCHEMBL22432192 0.73 CNR1 (0.44) NR3C2KDM4EMEN1KMT2AGAA
SCHEMBL158574 0.72 NR3C2 (0.60) NR3C2MEN1KMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO claimed
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO disclosed
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
EP-3919564-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919562-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919563-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
EP-2553021-B1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2014-05-07 EP disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
EP-2553021-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-02-06 EP disclosed
US-20100019210-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2010-01-28 US disclosed
WO-2009115535-A2 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009115536-A1 POLYAMIDE NANOCOMPOSITES WITH HYPER-BRANCHED POLYETHYLENIMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed