SCHEMBL465496

SCHEMBL465496

CCCCCCC(C)c1cc(C(C)(C)c2ccccc2)ccc1Nc1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.39
RORC P51449 1/20 0.37
ALDH1A1 P00352 2/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PRSS1 P07477 2/20 0.34
CTSG P08311 2/20 0.34
CTRB1 P17538 2/20 0.34
CMA1 P23946 2/20 0.34
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
MAP2K1 Q02750 1/20 0.32
HDAC8 Q9BY41 4/20 0.32
HDAC3 O15379 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465481 0.91 NR3C2 (0.40) NR3C2ALDH1A1KMT2AMEN1MAPT
SCHEMBL465363 0.85 RORC (0.52) NR3C2RORCALDH1A1KMT2AMEN1
SCHEMBL465362 0.84 MEN1 (0.36) NR3C2ALDH1A1KMT2AMEN1MAPT
SCHEMBL2364617 0.81 RORC (0.35) NR3C2RORCALDH1A1KMT2AMEN1
SCHEMBL28129178 0.78 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL11800482 0.77 KCNH3 (0.40) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL8621515 0.75 RORC (0.40) RORCALDH1A1KMT2AMEN1PRSS1
SCHEMBL8619588 0.75 RORC (0.40) RORCALDH1A1KMT2AMEN1PRSS1
SCHEMBL9403088 0.75 RORC (0.40) RORCALDH1A1
SCHEMBL9403082 0.75 RORC (0.49) RORCALDH1A1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO claimed
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO disclosed
EP-3919562-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919563-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919564-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
EP-2553021-B1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2014-05-07 EP disclosed
EP-2553021-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-02-06 EP disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
EP-2121843-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2009-11-25 EP disclosed
WO-2009115535-A2 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009115536-A1 POLYAMIDE NANOCOMPOSITES WITH HYPER-BRANCHED POLYETHYLENIMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
WO-2008074687-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2008-06-26 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed