SCHEMBL465481

SCHEMBL465481

CCCCCCC(C)c1ccccc1Nc1ccc(C(C)(C)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.40
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PRSS1 P07477 2/20 0.35
CTSG P08311 2/20 0.35
CTRB1 P17538 2/20 0.35
CMA1 P23946 2/20 0.35
HDAC8 Q9BY41 4/20 0.33
HDAC3 O15379 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAP2K1 Q02750 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
MMP2 P08253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465496 0.91 NR3C2 (0.39) NR3C2ALDH1A1KMT2AMEN1MAPT
SCHEMBL11800482 0.87 KCNH3 (0.40) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL18039253 0.82 MAPT (0.44) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL14191958 0.82 TDP1 (0.45) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL11800992 0.81 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL465362 0.77 MEN1 (0.36) NR3C2ALDH1A1KMT2AMEN1MAPT
SCHEMBL11129227 0.75 MAPT (0.41) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL28228152 0.74 CYSLTR2 (0.45) ALDH1A1KMT2AMEN1MAPTMAPK1
SCHEMBL465363 0.74 RORC (0.52) NR3C2ALDH1A1KMT2AMEN1MAPT
SCHEMBL28129178 0.72 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO claimed
WO-2023099128-A1 POLYAMIDE-BASED PRODUCTS LANXESS DEUTSCHLAND GMBH (DE) 2023-06-08 WO disclosed
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
EP-3919562-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919564-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919563-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
EP-2553021-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-02-06 EP disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-20100019210-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2010-01-28 US disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
EP-2049597-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2009-04-22 EP disclosed
WO-2008012233-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2008-01-31 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0586985-A1 Stabilized Polyamide/Polyphenylene ether mouldings BASF Aktiengesellschaft (DE) 1994-03-16 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed