Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544044 | 0.78 | — | — | |
| SCHEMBL465472 | 0.78 | — | — | |
| SCHEMBL465343 | 0.73 | — | — | |
| SCHEMBL2839300 | 0.70 | LMNA (0.44) | TSHR | |
| SCHEMBL24773119 | 0.69 | TSHR (0.35) | TSHR | |
| SCHEMBL9930065 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL7528495 | 0.67 | — | — | |
| SCHEMBL10660488 | 0.66 | TSHR (0.35) | TSHR | |
| SCHEMBL17866356 | 0.65 | SLC6A4 (0.37) | — | |
| SCHEMBL19937888 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4143009-A | POLYURETHANE-EPOXY CASTING RESIN | DEWEY FRANK | 1979-03-06 | — | — | US | claimed |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |
| US-8481652-B2 | Thermoplastic polyamides having polyether amines | BASF SE (DE) | 2013-07-09 | — | — | US | disclosed |
| WO-2012007301-A3 | FOAM ENHANCEMENT OF FATTY ACYL GLYCINATE SURFACTANTS | UNILEVER PLC (GB) | 2012-05-10 | — | — | WO | disclosed |
| EP-2257597-B1 | POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES | BASF SE (DE) | 2011-11-30 | — | — | EP | disclosed |
| EP-2227507-B1 | THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES | BASF SE (DE) | 2011-08-31 | — | — | EP | disclosed |
| US-20110021687-A1 | POLYAMIDE NANOCOMPOSITES WITH HYPER-BRANCHED POLYETHYLENEIMINES | BASF SE (DE) | 2011-01-27 | — | — | US | disclosed |
| WO-2009115535-A2 | POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES | BASF SE (DE) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009115536-A1 | POLYAMIDE NANOCOMPOSITES WITH HYPER-BRANCHED POLYETHYLENIMINES | BASF SE (DE) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009077492-A2 | THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009050094-A1 | THERMOPLASTIC POLYESTER MOLDING COMPOUNDS COMPRISING HIGHLY BRANCHED POLYETHER AMINES | BASF SE (DE) | 2009-04-23 | — | — | WO | disclosed |
| EP-0603716-A1 | Fast-curing, high strength, two-part sealants using acetoacetate-amine cure chemistry | TREMCO INCORPORATED (US) | 1994-06-29 | — | — | EP | disclosed |
| US-4239700-A | Isatoic anhydride derivatives and use as chain-extenders | TEXACO DEVELOPMENT CORP. (US) | 1980-12-16 | — | — | US | disclosed |
| US-4194070-A | Isatoic anhydride derivatives and use as chain-extenders | TEXACO DEVELOPMENT CORPORATION (US) | 1980-03-18 | — | — | US | disclosed |
| US-4191706-A | REACTION PRODUCT OF POLYOXYPROPYLENEPOLYAMINE AND ISATOIC ANHYDRIDE | TEXACO DEVELOPMENT CORP. (US) | 1980-03-04 | — | — | US | disclosed |
| US-4180644-A | Polyurethane chain-extenders | TEXACO DEVELOPMENT CORP. (US) | 1979-12-25 | — | — | US | disclosed |
| US-4143009-A | POLYURETHANE-EPOXY CASTING RESIN | DEWEY FRANK | 1979-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, MRPS18A | HDAC7 2253/4885HDAC8 990/4885HDAC6 3929/4885 |
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | HDAC7 2773/4885HDAC8 1248/4885HDAC6 4307/4885 |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | HDAC7 1873/4885HDAC8 869/4885HDAC6 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.